Photostimulated hole transport through a DNA duplex immobilized on a gold electrode

被引：75

作者：

Okamoto, A ^{[1
]}

Kamei, T

Tanaka, K

Saito, I

机构：

[1] Kyoto Univ, Fac Engn, Dept Synthet Chem & Biol Chem, Kyoto 6158510, Japan

[2] Japan Sci & Technol Corp, Koriyama, Fukushima 9638642, Japan

[3] Nihon Univ, Sch Engn, NEWCAT Inst, Tokyo 102, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 126卷 / 45期

关键词：

D O I：

10.1021/ja0449067

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Photostimulated hole transport through DNA duplexes immobilized on gold electrodes has been investigated. By modifying a gold electrode with a DNA duplex containing a photosensitizer, we have observed a sequence-dependent cathodic photocurrent. DNA acts as a good mediator for cathodic photocurrent when appropriate sequences are selected. Copyright © 2004 American Chemical Society.

引用

页码：14732 / 14733

页数：2

共 37 条

[1] Photochemistry of water-soluble quinones.: Production of the hydroxyl radical, singlet oxygen and the superoxide ion [J].

Alegría, AE ;

Ferrer, A ;

Santiago, G ;

Sepúlveda, E ;

Flores, W .

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 1999, 127 (1-3) :57-65

[2]

Alivisatos AP, 1998, ADV MATER, V10, P1297

[3] Long-range oxidation of guanine by Ru(III) in duplex DNA [J].

Arkin, MR ;

Stemp, EDA ;

Pulver, SC ;

Barton, JK .

CHEMISTRY & BIOLOGY, 1997, 4 (05) :389-400

[4] Photocleavage of nucleic acids [J].

Armitage, B .

CHEMICAL REVIEWS, 1998, 98 (03) :1171-1200

[5] Influence of intervening mismatches on long-range guanine oxidation in DNA duplexes [J].

Bhattacharya, PK ;

Barton, JK .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (36) :8649-8656

[6] Mutation detection by electrocatalysis at DNA-modified electrodes [J].

Boon, EM ;

Ceres, DM ;

Drummond, TG ;

Hill, MG ;

Barton, JK .

NATURE BIOTECHNOLOGY, 2000, 18 (10) :1096-1100

[7] An electrical probe of protein-DNA interactions on DNA-modified surfaces [J].

Boon, EM ;

Salas, JE ;

Barton, JK .

NATURE BIOTECHNOLOGY, 2002, 20 (03) :282-286

[8] Long-range oxidative damage in duplex DNA: the effect of bulged G in a G-C tract and tandem G/A mispairs [J].

Boone, E ;

Schuster, GB .

NUCLEIC ACIDS RESEARCH, 2002, 30 (03) :830-837

[9] Fundamentals in the design of molecular electronic devices: Long-range charge carrier transport and electronic coupling [J].

Fox, MA .

ACCOUNTS OF CHEMICAL RESEARCH, 1999, 32 (03) :201-207

[10] Long distance charge transport in DNA: The hopping mechanism [J].

Giese, B .

ACCOUNTS OF CHEMICAL RESEARCH, 2000, 33 (09) :631-636

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