Natural Products for the Prevention and Management of Helicobacter pylori Infection

被引：53
作者：
Liu, Qing [1 ]
Meng, Xiao [1 ]
Li, Ya [1 ]
Zhao, Cai-Ning [1 ]
Tang, Guo-Yi [1 ]
Li, Sha [1 ,2 ]
Gan, Ren-You [3 ]
Li, Hua-Bin [4 ]
机构：
[1] Sun Yat Sen Univ, Sch Publ Hlth, Dept Nutr, Guangdong Prov Key Lab Food Nutr & Hlth, Guangzhou 510080, Guangdong, Peoples R China
[2] Univ Hong Kong, Li Ka Shing Fac Med, Sch Chinese Med, Hong Kong, Hong Kong, Peoples R China
[3] Shanghai Jiao Tong Univ, Sch Agr & Biol, Dept Food Sci & Engn, Shanghai 200240, Peoples R China
[4] Sun Yat Sen Univ, South China Sea Bioresource Exploitat & Utilizat, Guangzhou 510006, Guangdong, Peoples R China
来源：
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY | 2018年 / 17卷 / 04期
基金：
中国国家自然科学基金;
关键词：
fruit; Helicobacter pylori; medicinal plant; spice; vegetable; IN-VITRO SUSCEPTIBILITY; DRUG-RESISTANT STRAINS; POSSESS ANTIMICROBIAL ACTIVITY; CELL-SURFACE HYDROPHOBICITY; STANDARD TRIPLE THERAPY; MUSCADINE GRAPE SKIN; ANTIBACTERIAL ACTIVITY; MEDICINAL-PLANTS; STEM BARK; ANTIADHESIVE PROPERTIES;
D O I：
10.1111/1541-4337.12355
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
Helicobacter pylori is the main pathogen that induces chronic gastritis, peptic ulcers, atrophic gastritis, and other gastric disorders, and it is classified as a group I carcinogen. To eradicate H. pylori infection, triple therapy consisting of two antibiotics and a proton pump inhibitor is the most widely recommended first-line therapeutic strategy. Antimicrobial resistance to antibiotics contained in triple therapy could lead to therapeutic regimen failures. Recent studies showed that many natural products, including fruits, vegetables, spices, and medicinal plants, possess inhibitory effects on H. pylori, indicating their potential to be alternatives to prevent and manage H. pylori infection. This review summarizes the effects of natural products on H. pylori infection and highlights the mechanisms of action.
引用
收藏
页码：937 / 952
页数：16
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