Gold(I)-Catalyzed Regioselective Cyclization to Access Cyclopropane-Fused Tetrahydrobenzochromenes

被引：13

作者：

Kumar, Perla Bharath ^{[1
,2
]}

Raju, Chittala Emmaniel ^{[1
,2
]}

Chandubhai, Patel Hinal ^{[1
]}

Sridhar, Balasubramanian ^{[3
]}

V. Karunakar, Galla ^{[1
,2
]}

机构：

[1] Indian Inst Chem Technol, Fluoro & Agrochem Div, CSIR, Hyderabad 500007, India

[2] Acad Sci & Innovat Res, Ghaziabad 201002, India

[3] Indian Inst Chem Technol, Ctr Xray Crystallog, CSIR, Hyderabad 500007, India

来源：

ORGANIC LETTERS | 2022年

关键词：

CATALYZED CYCLOISOMERIZATIONS; GOLD; ENYNES; LIGANDS;

D O I：

10.1021/acs.orglett.2c02564

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Molecules that are obtained from nature are known to exhibit several biological applications.1 In medicinal chemistry,2 agrochemicals,3 and material sciences,4 it has been observed that compounds containing heteroatoms such as nitrogen, oxygen, and sulfur in their core structures have a wide range of applications. Among them, oxygen-containing molecules such as chromenes and benzochromenes are found to have potential biological applications.5 For example, dihydro mollugin (A) shows antiviral activity6 and mollugin (B) exhibits mutagenic and recombinogenic activities,7 as shown in

引用

页码：6761 / 6766

页数：6

共 54 条

[51] Functional Materials: From Hard to Soft Porous Frameworks [J].

Thomas, Arne .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (45) :8328-8344

[52] 1,2-Migrations onto Gold Carbene Centers [J].

Wang, Tao ;

Hashmi, A. Stephen K. .

CHEMICAL REVIEWS, 2021, 121 (14) :8948-8978

[53] Gold(I)/Xiang-Phos-Catalyzed Asymmetric Intramolecular Cyclopropanation of Indenes and Trisubstituted Alkenes [J].

Zhang, Pei-Chao ;

Wang, Yidong ;

Zhang, Zhan-Ming ;

Zhang, Junliang .

ORGANIC LETTERS, 2018, 20 (22) :7049-7052

[54] Iridium-Catalyzed Cycloisomerization of N-Tethered 1,7-Enynes: Construction of an Azabicyclo[5.1.0]octene System [J].

Zhao, Sheng ;

Zang, Zhong-Lin ;

Li, Siyu ;

Wen, Xumei ;

Wang, Chenhui ;

Guo, Jian ;

He, Yun .

JOURNAL OF ORGANIC CHEMISTRY, 2020, 85 (14) :9321-9330

← 1 2 3 4 5 6 →