Clinical Features and Visual Acuity Outcomes in Culture-Positive Endogenous Fungal Endophthalmitis in Southern China

被引:15
作者
Duan, Fang [1 ]
Yang, Yao [1 ]
Yuan, Zhaohui [1 ]
Zheng, Yongxin [1 ]
Cheng, Zhixing [1 ]
Lin, Xiaofeng [1 ]
机构
[1] Sun Yat Sen Univ, State Key Lab Ophthalmol, Zhongshan Ophthalm Ctr, Guangzhou 510060, Guangdong, Peoples R China
基金
中国国家自然科学基金;
关键词
INFECTIOUS ENDOPHTHALMITIS; ASPERGILLUS; EXPERIENCE; MANAGEMENT;
D O I
10.1155/2017/3483497
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose. To report the causative organisms, management strategies, and visual outcomes of culture-proven endogenous fungal endophthalmitis in a case series from southern China. Methods. We reviewed the microbiological and medical records of patients with culture-positive endogenous fungal endophthalmitis visiting the Zhongshan Ophthalmic Center, Guangzhou, China, between January 1, 2006, and March 31, 2016. Results. The inclusion criteria were met in 32 eyes of 29 patients. Molds were a common causative organism in 15 patients (51.7%), while yeasts appeared in 14 patients (48.3%). Initial visual acuity (VA) at the level of finger counting or better was significantly related to a good visual outcome (P = 0 002). Molds as a causative agent were significantly associated with worse visual outcome than yeasts (P = 0 020). Conclusion. Molds were a common cause of culture-proven fungal endophthalmitis. Endogenous fungal endophthalmitis is generally associated with poor VA outcomes, especially if caused by molds and if the patient's initial VA is too low to permit finger counting.
引用
收藏
页数:5
相关论文
共 26 条
[1]   Infectious endophthalmitis: review of 420 cases [J].
Bhoomibunchoo, Chavakij ;
Ratanapakorn, Tanapat ;
Sinawat, Suthasinee ;
Sanguansak, Thuss ;
Moontawee, Kittipatra ;
Yospaiboon, Yosanan .
CLINICAL OPHTHALMOLOGY, 2013, 7 :247-252
[2]   Endogenous Endophthalmitis - An 18-year review of culture-positive cases at a tertiary care center [J].
Binder, MI ;
Chua, J ;
Kaiser, PK ;
Procop, GW ;
Isada, CM .
MEDICINE, 2003, 82 (02) :97-105
[3]   Endogenous endophthalmitis: 10-year experience at a tertiary referral centre [J].
Connell, P. P. ;
O'Neill, E. C. ;
Fabinyi, D. ;
Islam, F. M. A. ;
Buttery, R. ;
McCombe, M. ;
Essex, R. W. ;
Roufail, E. ;
Clark, B. ;
Chiu, D. ;
Campbell, W. ;
Allen, P. .
EYE, 2011, 25 (01) :66-72
[4]   Addressing antibiotic abuse in China: An experimental audit study [J].
Currie, Janet ;
Lin, Wanchuan ;
Meng, Juanjuan .
JOURNAL OF DEVELOPMENT ECONOMICS, 2014, 110 :39-51
[5]   INHIBITION OF MONOCYTE-MEDIATED DAMAGE TO FUNGAL HYPHAE BY STEROID-HORMONES [J].
DIAMOND, RD .
JOURNAL OF INFECTIOUS DISEASES, 1983, 147 (01) :160-160
[6]   Causative Microorganisms of Infectious Endophthalmitis: A 5-Year Retrospective Study [J].
Duan, Fang ;
Wu, Kaili ;
Liao, Jingyu ;
Zheng, Yongxin ;
Yuan, Zhaohui ;
Tan, Junlian ;
Lin, Xiaofeng .
JOURNAL OF OPHTHALMOLOGY, 2016, 2016
[7]   Infectious endophthalmitis: clinical features, management and visual outcomes [J].
Fan, Jennifer C. ;
Niederer, Rachael L. ;
von Lany, Hirut ;
Polkinghorne, Philip J. .
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2008, 36 (07) :631-636
[8]   ENDOGENOUS ENDOPHTHALMITIS CAUSED BY CANDIDA-ALBICANS IN A HEALTHY WOMAN [J].
KOSTICK, DA ;
FOSTER, RE ;
LOWDER, CY ;
MEYERS, SM ;
MCHENRY, MC .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 1992, 113 (05) :593-595
[9]   Endophthalmitis [J].
Kresloff, MS ;
Castellarin, AA ;
Zarbin, MA .
SURVEY OF OPHTHALMOLOGY, 1998, 43 (03) :193-224
[10]   CHANGES IN THE CLINICAL FEATURES AND PROGNOSTIC FACTORS OF ENDOGENOUS ENDOPHTHALMITIS Fifteen Years of Clinical Experience in Korea [J].
Lee, Suhwan ;
Um, Taewoong ;
Joe, Soo Geun ;
Hwang, Jong-Uk ;
Kim, June-Gone ;
Yoon, Young Hee ;
Lee, Joo Yong .
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 2012, 32 (05) :977-984