Microwave Absorbing Fe3O4@mTiO2 Nanoparticles as an Intelligent Drug Carrier for Microwave-Triggered Synergistic Cancer Therapy

被引：14

作者：

Peng, Hongxia ^{[1
]}

Hu, Jilin ^{[1
]}

Hu, Chuanyue ^{[1
]}

Wu, Tengyan ^{[1
]}

Tian, Xiuying ^{[1
]}

机构：

[1] Hunan Univ Humanities Sci & Technol, Hunan Prov Key Lab Fine Ceram & Powder Mat, Loudi 137400, Hunan Province, Peoples R China

来源：

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY | 2017年 / 17卷 / 08期

关键词：

Fe3O4@mTiO(2); Mesoporous; Magnetic; Microwave Thermal Therapy; Chemotherapy; Homogeneous Precipitation Method; ABSORPTION PROPERTIES; IRON-OXIDE; DELIVERY; SHELL; RELEASE; NANOCOMPOSITE; NANOCARRIER; ENRICHMENT; POLYMER;

D O I：

10.1166/jnn.2017.13809

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Herein a novel multifunctional nanoplatform based on Fe3O4@mTiO(2) (m was short for mesoporous) nanoparticles is developed for effective microwave-triggered synergistic cancer therapy. Fe3O4@mTiO(2) nanoparticles employed in the study not only function as microwave absorbing agents but also as nanocarriers with a high drug loading efficiency. Fe3O4 core confers the system biocompatibility and cells targeting ability. Moreover, mTiO(2) shell as drug carriers with a high drug loading efficiency and loading drug can controlled release on the microwave irradiation. By combining these capabilities, the multifunctional nanoparticles show an effective therapeutic efficiency toward the target cells.

引用

收藏

页码：5139 / 5146

页数：8

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