Natural killer cells and viral infections

被引：230
作者：
French, AR [1 ]
Yokoyama, WM [1 ]
机构：
[1] Washington Univ, Med Ctr, Div Rheumatol, Howard Hughes Med Inst, St Louis, MO 63110 USA
来源：
CURRENT OPINION IN IMMUNOLOGY | 2003年 / 15卷 / 01期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/S095279150200002X
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Natural killer (NK) cells play a key role in innate host defense against viruses. Significant progress has been made in understanding the specific response of NK cells during viral infections by the recent identification of an NK cell receptor involved in in vivo resistance, and its ligand. New insight has also been provided in NK cell cytokine and chemokine responses, highlighting the complexity of regulatory pathways. Taken together, a more comprehensive view of the role of NK cells in innate immunity is now available.
引用
收藏
页码：45 / 51
页数：7
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