ANTIVIRAL COMPOUNDS IN THE PIPELINE TO TACKLE H1N1 INFLUENZA INFECTION

被引：6
|
作者：
Beigel, J. H. [1 ]
机构：
[1] NCI, Immunoregulat Lab, Div Intramural Res, NIAID,SAIC Frederick Inc,NIH, Frederick, MD 21702 USA
来源：
DRUGS OF THE FUTURE | 2010年 / 35卷 / 05期
基金：
美国国家卫生研究院;
关键词：
CYCLOPENTANE NEURAMINIDASE INHIBITORS; IN-VIVO ACTIVITIES; A VIRUS-INFECTION; H5N1; VIRUS; PASSIVE IMMUNOTHERAPY; CELL-CULTURE; OSELTAMIVIR; EFFICACY; COMBINATION; ZANAMIVIR;
D O I：
10.1358/dof.2010.035.05.1487081
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The recent pandemic of H1N1 has demonstrated the potential vulnerability of the human population to novel influenza viruses. While there is recent increased interest and effort in developing effective anti-influenza agents, few new products have entered clinical studies. This review will highlight the limited armamentarium of licensed influenza agents, and discuss novel compounds and strategies that have entered clinical studies and may therefore be imminently available to the treating clinician.
引用
收藏
页码：385 / 392
页数：8
相关论文
共 50 条
  • [1] H1N1 Influenza A infection
    Dotis, J.
    Roilides, E.
    HIPPOKRATIA, 2009, 13 (03) : 135 - 138
  • [2] Treatment of oseltamivir-resistant influenza A (H1N1) virus infections in mice with antiviral agents
    Smee, Donald F.
    Julander, Justin G.
    Tarbet, E. Bart
    Gross, Matthew
    Jack Nguyen
    ANTIVIRAL RESEARCH, 2012, 96 (01) : 13 - 20
  • [3] The Identification Distinct Antiviral Factors Regulated Influenza Pandemic H1N1 Infection
    Wang, Baoxin
    Zheng, Hao
    Dong, Xia
    Zhang, Wenhua
    Wu, Junjing
    Chen, Hongbo
    Zhang, Jing
    Zhou, Ao
    INTERNATIONAL JOURNAL OF MICROBIOLOGY, 2024, 2024
  • [4] Evaluation of Influenza A H1N1 infection and antiviral utilization in a tertiary care hospital
    Talita Rantin Belucci
    Alexandre R. Marra
    Michael B. Edmond
    João Renato Rebello Pinho
    Paula Kiyomi Onaga Yokota
    Ana Carolina Cintra Nunes Mafra
    Oscar Fernando Pavão dos Santos
    BMC Infectious Diseases, 18
  • [5] Evaluation of Influenza A H1N1 infection and antiviral utilization in a tertiary care hospital
    Belucci, Talita Rantin
    Marra, Alexandre R.
    Edmond, Michael B.
    Rebello Pinho, Joao Renato
    Onaga Yokota, Paula Kiyomi
    Cintra Nunes Mafra, Ana Carolina
    Pavao dos Santos, Oscar Fernando
    BMC INFECTIOUS DISEASES, 2018, 18
  • [6] Antiviral and anti-inflammatory activity of arbidol hydrochloride in influenza A (H1N1) virus infection
    Liu, Qiang
    Xiong, Hai-rong
    Lu, Li
    Liu, Yuan-yuan
    Luo, Fan
    Hou, Wei
    Yang, Zhan-qiu
    ACTA PHARMACOLOGICA SINICA, 2013, 34 (08) : 1075 - 1083
  • [7] The novel influenza A/H1N1 or (2009) Influenza A/H1N1 or "Swine-origin influenza A (H1N1)"
    Cabezas Fernandez del Campo, Jose Antonio
    ANALES DE LA REAL ACADEMIA NACIONAL DE FARMACIA, 2009, 75 (04): : 947 - 963
  • [8] Triple-Combination Antiviral Drug for Pandemic H1N1 Influenza Virus Infection in Critically Ill Patients on Mechanical Ventilation
    Kim, Won-Young
    Suh, Gee Young
    Huh, Jin Won
    Kim, Sung-Han
    Kim, Min-ju
    Kim, Yun Seong
    Kim, Hye-Ryoun
    Ryu, Yon Ju
    Han, Min Soo
    Ko, Young Gwan
    Chon, Gyu Rak
    Lee, Kwan Ho
    Choi, Sang-Ho
    Hong, Sang-Bum
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2011, 55 (12) : 5703 - 5709
  • [9] Evaluation of the antiviral potential of gemini surfactants against influenza virus H1N1
    Khodsiani, Mehrnaz
    Kianmehr, Zahra
    Brycki, Bogumil
    Szulc, Adrianna
    Mehrbod, Parvaneh
    ARCHIVES OF MICROBIOLOGY, 2023, 205 (05)
  • [10] Alloferon and Zanamivir Show Effective Antiviral Activity against Influenza A Virus (H1N1) Infection In Vitro and In Vivo
    Lee, Dahae
    Jo, Hyejung
    Jang, Yoojin
    Bae, Suhyun
    Agura, Tomoyo
    Kang, Dongmin
    Kang, Minsoo
    Kim, Yuri
    Cho, Nam-Hyuk
    Kim, Yejin
    Kang, Jae Seung
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (01)
12345