Centenarians Differ in Their Comorbidity Trends During The 6 Years Before Death Compared to Individuals Who Died in Their 80s or 90s

被引:27
作者
Gellert, Paul [1 ]
von Berenberg, Petra [1 ,2 ]
Oedekoven, Monika [1 ]
Klemt, Maria [1 ]
Zwillich, Christine [3 ]
Hoerter, Stefan [3 ]
Kuhlmey, Adelheid [1 ]
Draeger, Dagmar [1 ]
机构
[1] Charite Univ Med Berlin, Inst Med Sociol & Rehabil Sci, Luisenstr 13, D-10117 Berlin, Germany
[2] Charite Univ Med Berlin, Dept Gen Visceral & Vasc Surg, Berlin, Germany
[3] Inst Hlth Care Res Knappschaft, Bochum, Germany
来源
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES | 2018年 / 73卷 / 10期
关键词
Longevity; Multimorbidity; Health services; Trajectory; Distance-to-death; COGNITIVE FUNCTION; COHORTS BORN; LIFE-SPAN; MORBIDITY; DISEASE; HEALTH; OLDER; AGE; SUPERCENTENARIANS; COMPRESSION;
D O I
10.1093/gerona/glx136
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Background: While compression of morbidity has now been studied in multiple cohorts, we hypothesize that centenarians might also have fewer chronic conditions as well. We assume that individuals who die as centenarians have less comorbidities and have a less steep rise of the number of comorbidities over the final years before death compared to those who died as nonagenarians (90-99 years) or octogenarians (80-89 years of age). Methods: This German cohort study used health insurance data. The data contain complete information on diagnoses and health care transactions for the 6 years prior to death. The sample (N = 1,398; 34,735-person calendar quarters) is comprised of three groups of individuals; those who died as centenarians were compared with random samples of individuals who died as nonagenarians or as octogenarians. Community-dwelling and institutionalized individuals were included. Results: One quarter prior to death, individuals who died as centenarians had, on average, 3.3 comorbidities. Octogenarians had 4.6 comorbiditics one quarter prior to death. Further, there was a significant time-to-death by age-at-death interaction (B = -.03, p < .001), where centenarians showed a less steep increase in the number of comorbidities than the comparison groups in their last 6 years prior to death. Conclusions: The lower prevalence of comorbidities in individuals who died as centenarians compared with those who died at a younger age reinforces the notion of centenarians as a selective group. Avoiding the confounding and potentially synergistic effects of having multiple chronic illnesses is likely vital to being able to survive to extreme ages.
引用
收藏
页码:1357 / 1362
页数:6
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