Copper-Catalyzed Cyanation of Heterocycle Carbon-Hydrogen Bonds

被引：138

作者：

Do, Hien-Quang ^{[1
]}

Daugulis, Olafs ^{[1
]}

机构：

[1] Univ Houston, Dept Chem, Houston, TX 77204 USA

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 11期

关键词：

C-H BONDS; HETEROAROMATIC-COMPOUNDS; ARYL HALIDES; DIRECT ARYLATION; FUNCTIONALIZATION; INDOLES; BROMIDES; CYANIDE;

D O I：

10.1021/ol100772u

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A method for regioselective cyanation of heterocycles has been developed. A number of aromatic heterocycles as well as azulene can be cyanated in reasonable to good yields by using a copper cyanide catalyst and an iodine oxidant.

引用

页码：2517 / 2519

页数：3

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