Hemodynamic and symptomatic improvement after delayed thrombolysis with Reteplase in a patient with massive bilateral pulmonary emboli

被引:3
作者
Sharif-Kashani, Babak [1 ]
Kiani, Arda [2 ]
Bakhshayesh-Karam, Mehrdad [3 ]
Sheybani-Afshar, Faezeh [1 ]
Behzadnia, Neda [4 ]
Naghash-Zadeh, Farah [1 ]
机构
[1] Shahid Beheshti Univ Med Sci, Natl Res Inst TB & Lung Dis NRITLD, Lung Transplantat Res Ctr, Tehran, Iran
[2] Shahid Beheshti Univ Med Sci, Natl Res Inst TB & Lung Dis NRITLD, Tracheal Dis Res Ctr, Tehran, Iran
[3] Shahid Beheshti Univ Med Sci, Natl Res Inst TB & Lung Dis NRITLD, Pediat Resp Dis Res Ctr, Tehran, Iran
[4] Shahid Beheshti Univ Med Sci, Natl Res Inst TB & Lung Dis NRITLD, Chron Resp Dis Res Ctr, Tehran, Iran
关键词
delayed diagnosis; pulmonary embolism; thrombolytic therapy; HYPERTENSION; DIAGNOSIS; GUIDELINES; MANAGEMENT;
D O I
10.1097/MBC.0000000000000087
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Most patients surviving the acute phase of pulmonary embolism will recover with no residue. But, 2-4% of patients will progress to chronic thromboembolic pulmonary hypertension. In this group, usually a Honey moon' period is seen but a few may show progression with ongoing symptoms despite medical treatment. In this case report, we review a patient in whom delayed thrombolytic therapy was administered due to progressive symptoms after 21 days. Her condition was stabilized. The early posttreatment computed tomographic pulmonary angiography (CTPA) showed incomplete resolution, but after 6 months she was functional class I with a normal CTPA and echocardiography. (C) 2015 Wolters Kluwer Health, Inc. All rights reserved.
引用
收藏
页码:88 / 90
页数:3
相关论文
共 15 条
[1]  
[Anonymous], EUR RESP J S
[2]   The mortality of untreated pulmonary embolism in emergency department patients [J].
Calder, KK ;
Herbert, M ;
Henderson, SO .
ANNALS OF EMERGENCY MEDICINE, 2005, 45 (03) :302-310
[3]   Pulmonary embolism: What have we learned since Virchow? - Natural history, pathophysiology, and diagnosis [J].
Dalen, JE .
CHEST, 2002, 122 (04) :1440-1456
[4]   Relation of duration of symptoms with response to thrombolytic therapy in pulmonary embolism [J].
Daniels, LB ;
Parker, JA ;
Patel, SR ;
Grodstein, F ;
Goldhaber, SZ .
AMERICAN JOURNAL OF CARDIOLOGY, 1997, 80 (02) :184-188
[5]   Impact of Delay in Clinical Presentation on the Diagnostic Management and Prognosis of Patients with Suspected Pulmonary Embolism [J].
den Exter, Paul L. ;
van Es, Josien ;
Erkens, Petra M. G. ;
van Roosmalen, Mark J. G. ;
van den Hoven, Pim ;
Hovens, Marcel M. C. ;
Kamphuisen, Pieter W. ;
Klok, Frederikus A. ;
Huisman, Menno V. .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2013, 187 (12) :1369-1373
[6]  
ELLIOTT CG, 1992, CHEST, V101, pS163, DOI 10.1378/chest.101.4_Supplement.163S
[7]   Guidelines for the diagnosis and treatment of pulmonary hypertension [J].
Galie, Nazzareno ;
Hoeper, Marius M. ;
Humbert, Marc ;
Torbicki, Adam ;
Vachiery, Jean-Luc ;
Albert Barbera, Joan ;
Beghetti, Maurice ;
Corris, Paul ;
Gaine, Sean ;
Gibbs, J. Simon ;
Angel Gomez-Sanchez, Miguel ;
Jondeau, Guillaume ;
Klepetko, Walter ;
Opitz, Christian ;
Peacock, Andrew ;
Rubin, Lewis ;
Zellweger, Michael ;
Simonneau, Gerald .
EUROPEAN HEART JOURNAL, 2009, 30 (20) :2493-2537
[8]   Pulmonary embolism and deep vein thrombosis [J].
Goldhaber, Samuel Z. ;
Bounameaux, Henri .
LANCET, 2012, 379 (9828) :1835-1846
[9]   Chronic thromboembolic pulmonary hypertension [J].
Hoeper, MM ;
Mayer, E ;
Simonneau, G ;
Rubin, LJ .
CIRCULATION, 2006, 113 (16) :2011-2020
[10]   Acute Pulmonary Embolism [J].
Konstantinides, Stavros .
NEW ENGLAND JOURNAL OF MEDICINE, 2008, 359 (26) :2804-2813