A direct comparison of porcine (Strattice™) and bovine (Surgimend™) acellular dermal matrices in implant-based immediate breast reconstruction

被引：29
作者：
Ball, Jessica F. [1 ]
Sheena, Yezen [1 ]
Saleh, Dina M. Tarek [1 ]
Forouhi, Parto [2 ]
Benyon, Sarah L. [1 ,2 ]
Irwin, Michael S. [1 ,2 ]
Malata, Charles M. [1 ,2 ,3 ,4 ]
机构：
[1] Cambridge Univ Hosp NHS Fdn Trust, Addenbrookes Hosp, Dept Plast & Reconstruct Surg, Hills Rd, Cambridge CB2 0QQ, England
[2] Cambridge Univ Hosp NHS Fdn Trust, Addenbrookes Hosp, Cambridge Breast Unit, Hills Rd, Cambridge CB2 0QQ, England
[3] Anglia Ruskin Univ, Fac Med Sci, Postgrad Med Inst, Cambridge, England
[4] Anglia Ruskin Univ, Fac Med Sci, Postgrad Med Inst, Chelmsford, Essex, England
来源：
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY | 2017年 / 70卷 / 08期
关键词：
Acellular dermal matrix; Strattice; Surgimend; Implant; Breast reconstruction; SURGERY;
D O I：
10.1016/j.bjps.2017.05.015
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
Introduction: Acellular dermal matrix (ADM) assisted implant-based breast reconstruction (IBBR) has grown in popularity over traditional submuscular techniques. Numerous human, bovine or porcine derived ADMs are available with the type used varying considerably worldwide. Yet, comparative evidence for the efficacy of different ADMs particularly xenogenic is limited. This study directly compares early outcomes of porcine (Strattice (TM)) and bovine (Surgimend (TM)) ADMs in IBBR. Method: Retrospective study of sequential experience of immediate IBBR using Strattice or Surgimend ADM. Data was collected for patients undergoing ADM assisted IBBR after prophylactic or therapeutic mastectomy in Cambridge (October 2011-March 2016). Patient demographics, adjuvant and neoadjuvant therapies, operative details, postoperative management and outcomes were analysed. Key results: Total of 81 patients underwent IBBR with ADM; 38 bilateral and 43 unilateral (n = 119 breasts). Strattice was used in 30 breasts (25%) and Surgimend in 89 (75%). Analysis of patient specific variables showed statistical significance only for higher mastectomy weight in the Strattice group (367.1 +/- 159.3 g versus 296.3 +/- 133.4 g; P = 0.0379). Strattice was associated with higher rates of skin erythema post-operatively (16.7% versus 4.5%; P = 0.044). Analysed per woman or per breast, there was no statistically significant difference in rates of haematoma, infection, wound dehiscence, skin necrosis or seroma, although there was a trend towards more complications with Strattice. Conclusion: This study found significantly higher rates of skin erythema and a trend towards higher complication rates with Strattice in IBBR. Randomised controlled trials comparing different ADM outcomes are needed to inform best practice. (C) 2017 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：1076 / 1082
页数：7
相关论文
共 21 条
[1]   Bovine versus Porcine Acellular Dermal Matrix: A Comparison of Mechanical Properties [J].
Adelman, David M. ;
Selber, Jesse C. ;
Butler, Charles E. .
PLASTIC AND RECONSTRUCTIVE SURGERY-GLOBAL OPEN, 2014, 2 (05)
[2]   Outcome of the use of acellular-dermal matrix to assist implant-based breast reconstruction in a single centre [J].
Barber, M. D. ;
Williams, L. ;
Anderson, E. D. C. ;
Neades, G. T. ;
Raine, C. ;
Young, O. ;
Kulkarni, D. ;
Young, I. ;
Dixon, J. M. .
EJSO, 2015, 41 (01) :100-105
[3]  
Cornwell Kevin G, 2009, Clin Podiatr Med Surg, V26, P507, DOI 10.1016/j.cpm.2009.08.001
[4]   Single-stage breast reconstruction using Strattice™: A retrospective study [J].
Dikmans, R. E. G. ;
El Morabit, F. ;
Ottenhof, M. J. ;
Tuinder, S. M. H. ;
Twisk, J. W. R. ;
Moues, C. ;
Bouman, M. B. ;
Mullender, M. G. .
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY, 2016, 69 (02) :227-233
[5]   A Head-to-head Comparison between SurgiMend and Epiflex in 127 Breast Reconstructions [J].
Eichler, Christian ;
Vogt, Nadine ;
Brunnert, Klaus ;
Sauerwald, Axel ;
Puppe, Julian ;
Warm, Mathias .
PLASTIC AND RECONSTRUCTIVE SURGERY-GLOBAL OPEN, 2015, 3 (06)
[6]   Experimental evaluation of four biologic prostheses for ventral hernia repair [J].
Gaertner, Wolfgang B. ;
Bonsack, Margaret E. ;
Delaney, John P. .
JOURNAL OF GASTROINTESTINAL SURGERY, 2007, 11 (10) :1275-1285
[7]   AlloDerm and Strattice in Breast Reconstruction: A Comparison and Techniques for Optimizing Outcomes [J].
Glasberg, Scot B. ;
Light, David .
PLASTIC AND RECONSTRUCTIVE SURGERY, 2012, 129 (06) :1223-1233
[8]   A Systematic Review and Meta-Analysis of Complications Associated With Acellular Dermal Matrix-Assisted Breast Reconstruction [J].
Ho, Goretti ;
Nguyen, T. JoAnna ;
Shahabi, Ahva ;
Hwang, Brian H. ;
Chan, Linda S. ;
Wong, Alex K. .
ANNALS OF PLASTIC SURGERY, 2012, 68 (04) :346-356
[9]   Acellular Dermal Matrices in Breast Surgery A Comprehensive Review [J].
Ibrahim, Ahmed M. S. ;
Ayeni, Olubimpe A. ;
Hughes, Kenneth B. ;
Lee, Bernard T. ;
Slavin, Sumner A. ;
Lin, Samuel J. .
ANNALS OF PLASTIC SURGERY, 2013, 70 (06) :732-738
[10]   Findings of a national comparative audit of mastectomy and breast reconstruction surgery in England [J].
Jeevan, Ranjeet ;
Cromwell, David A. ;
Browne, John P. ;
Caddy, Christopher M. ;
Pereira, Jerome ;
Sheppard, Carmel ;
Greenaway, Kimberley ;
van der Meulen, Jan H. P. .
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY, 2014, 67 (10) :1333-1344
123