New norlignans and flavonoids of Dysosma versipellis

被引：11

作者：

Zheng, Yue ^{[1
]}

Xie, Yang-Guo ^{[1
]}

Zhang, Yu ^{[1
]}

Li, Tao ^{[3
]}

Li, Hui-Liang ^{[2
]}

Yan, Shi-Kai ^{[2
]}

Jin, Hui-Zi ^{[1
]}

Zhang, Wei-Dong ^{[1
,2
]}

机构：

[1] Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China

[2] Second Mil Med Univ, Dept Phytochem, Shanghai 200433, Peoples R China

[3] Shanghai Vet Res Inst, Minist Agr, Key Lab Anim Parasitol, Shanghai, Peoples R China

来源：

PHYTOCHEMISTRY LETTERS | 2016年 / 16卷

关键词：

Dysosma versipellis; Flavonoid; Norlignan; Antibacterial properties; LIGNANS; PODOPHYLLOTOXIN; DERIVATIVES;

D O I：

10.1016/j.phytol.2016.03.001

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new norlignans, dysosmanorlignans A and B (1-2); six new flavonoids, dysosmaflavones A-F (3-8); and 30 known compounds (9-38) were isolated from the roots of Dysosma versipellis. Their structures were determined by detailed analysis of MS and NMR spectroscopic data. Dysosmaflavones E and F both exhibited mild antibacterial activities against Streptococcus agalactiae, Pseudomonas aeruginosa, and Bacillus subtilis with MIC values ranging from 93.0 to 93.8 mu g/mL. (C) 2016 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.

引用

页码：75 / 81

页数：7

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