New norlignans and flavonoids of Dysosma versipellis

被引：11
|
作者：
Zheng, Yue [1 ]
Xie, Yang-Guo [1 ]
Zhang, Yu [1 ]
Li, Tao [3 ]
Li, Hui-Liang [2 ]
Yan, Shi-Kai [2 ]
Jin, Hui-Zi [1 ]
Zhang, Wei-Dong [1 ,2 ]
机构：
[1] Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China
[2] Second Mil Med Univ, Dept Phytochem, Shanghai 200433, Peoples R China
[3] Shanghai Vet Res Inst, Minist Agr, Key Lab Anim Parasitol, Shanghai, Peoples R China
来源：
PHYTOCHEMISTRY LETTERS | 2016年 / 16卷
关键词：
Dysosma versipellis; Flavonoid; Norlignan; Antibacterial properties; LIGNANS; PODOPHYLLOTOXIN; DERIVATIVES;
D O I：
10.1016/j.phytol.2016.03.001
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two new norlignans, dysosmanorlignans A and B (1-2); six new flavonoids, dysosmaflavones A-F (3-8); and 30 known compounds (9-38) were isolated from the roots of Dysosma versipellis. Their structures were determined by detailed analysis of MS and NMR spectroscopic data. Dysosmaflavones E and F both exhibited mild antibacterial activities against Streptococcus agalactiae, Pseudomonas aeruginosa, and Bacillus subtilis with MIC values ranging from 93.0 to 93.8 mu g/mL. (C) 2016 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码：75 / 81
页数：7
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