Patterning of cells on a PVC film surface functionalized by ion irradiation

被引：10
作者：
Jung, Chan-Hee [1 ]
Hwang, In-Tae [1 ]
Kwon, Ho-Je [1 ]
Nho, Young-Chang [1 ]
Choi, Jae-Hak [1 ]
机构：
[1] Korea Atom Energy Res Inst, Adv Radiat Technol Inst, Radiat Res Div Ind & Environm, Jeongeup Si 580185, Jeollabuk Do, South Korea
来源：
POLYMERS FOR ADVANCED TECHNOLOGIES | 2010年 / 21卷 / 02期
关键词：
ion irradiation; surface modification; poly(vinyl chloride); cell patterning; POLY(VINYL CHLORIDE); PLASMA; IMPLANTATION; IMPROVEMENT;
D O I：
10.1002/pat.1437
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Micropatterns of cells on a poly(vinyl chloride) (PVC) film surface were created by using ion irradiation. A PVC film was irradiated with H+ ions through a pattern mask in order to create patterns of the hydrophilic/hydrophobic regions on the PVC surface. The effect of ion irradiation on the surface properties of the PVC film was characterized by using Fourier transform-infrared spectroscopy (FT-IR), water contact angle measurement, and X-ray photoelectron spectroscopy (XPS). The results revealed that the chemical environment of the PVC film surface was effectively changed by ion irradiation due to dehydrochlorination and oxidation. The in vitro cell culture on the patterned PVC film surface showed selective adhesion and proliferation of the cells on the ion-irradiated regions. Well-defined 50 mu m patterns of the cells were obtained on the PVC film surface irradiated to 1 x 10(15) ions/cm(2). Copyright (C) 2009 John Wiley & Sons, Ltd.
引用
收藏
页码：135 / 138
页数：4
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