Crystal structure of the noncompetitive xylanase inhibitor TLXI, member of the small thaumatin-like protein family

被引：16

作者：

Vandermarliere, Elien ^{[2
]}

Lammens, Willem ^{[2
,3
]}

Schoepe, Jan ^{[2
]}

Rombouts, Sigrid ^{[4
]}

Fierens, Ellen

Gebruers, Kurt

Volckaert, Guido ^{[4
]}

Rabijns, Anja ^{[2
]}

Delcour, Jan A.

Strelkov, Sergei V. ^{[2
]}

Courtin, Christophe M. ^{[1
]}

机构：

[1] Katholieke Univ Leuven, Dept Mol & Microbial Syst, Lab Food Chem & Biochem, B-3001 Heverlee, Belgium

[2] Dept Pharmaceut Sci, Lab Biocrystallog, B-3000 Louvain, Belgium

[3] Dept Biol, Lab Mol Plant Physiol, B-3001 Louvain, Belgium

[4] Dept Biosyst, Lab Gene Technol, B-3001 Louvain, Belgium

来源：

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS | 2010年 / 78卷 / 10期

关键词：

xylanase inhibitor; thaumatin-like proteins; crystal structure; acidic surface cleft; WHEAT; RESOLUTION; TAXI;

D O I：

10.1002/prot.22737

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：2391 / 2394

页数：4

共 23 条

[1] THE CCP4 SUITE - PROGRAMS FOR PROTEIN CRYSTALLOGRAPHY [J].

BAILEY, S .

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 1994, 50 :760-763

[2] Variability of polymorphic families of three types of xylanase inhibitors in the wheat grain proteome [J].

Croes, Evi ;

Gebruers, Kurt ;

Robben, Johan ;

Noben, Jean-Paul ;

Samyn, Bart ;

Debyser, Griet ;

Van Beeumen, Jozef ;

Delcour, Jan A. ;

Courtin, Christophe M. .

PROTEOMICS, 2008, 8 (08) :1692-1705

[3] MolProbity: all-atom contacts and structure validation for proteins and nucleic acids [J].

Davis, Ian W. ;

Leaver-Fay, Andrew ;

Chen, Vincent B. ;

Block, Jeremy N. ;

Kapral, Gary J. ;

Wang, Xueyi ;

Murray, Laura W. ;

Arendall, W. Bryan, III ;

Snoeyink, Jack ;

Richardson, Jane S. ;

Richardson, David C. .

NUCLEIC ACIDS RESEARCH, 2007, 35 :W375-W383

[4] Triticum aestivum xylanase inhibitor (TAXI), a new class of enzyme inhibitor affecting breadmaking performance [J].

Debyser, W ;

Peumans, WJ ;

Van Damme, EJM ;

Delcour, JA .

JOURNAL OF CEREAL SCIENCE, 1999, 30 (01) :39-43

[5]

DEVOS AM, 1985, P NATL ACAD SCI USA, V82, P1406

[6] Coot:: model-building tools for molecular graphics [J].

Emsley, P ;

Cowtan, K .

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2004, 60 :2126-2132

[7] Xylanase inhibitors bind to nonstarch polysaccharides [J].

Fierens, Ellen ;

Gebruers, Kurt ;

Courtin, Christophe M. ;

Delcour, Jan A. .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2008, 56 (02) :564-570

[8] TLXI, a novel type of xylanase inhibitor from wheat (Triticum aestivum) belonging to the thaumatin family [J].

Fierens, Ellen ;

Rombouts, Sigrid ;

Gebruers, Kurt ;

Goesaert, Hans ;

Brijs, Kristof ;

Beaugrand, Johnny ;

Volckaert, Guido ;

Van Campenhout, Steven ;

Proost, Paul ;

Courtin, Christophe M. ;

Delcour, Jan A. .

BIOCHEMICAL JOURNAL, 2007, 403 :583-591

[9] Triticum aestivum L. endoxylanase inhibitor (TAXI) consists of two inhibitors, TAXI I and TAXI II, with different specificities [J].

Gebruers, K ;

Debyser, W ;

Goesaert, H ;

Proost, P ;

Van Damme, J ;

Delcour, JA .

BIOCHEMICAL JOURNAL, 2001, 353 :239-244

[10] A scheme for designating enzymes that hydrolyse the polysaccharides in the cell walls of plants [J].

Henrissat, B ;

Teeri, TT ;

Warren, RAJ .

FEBS LETTERS, 1998, 425 (02) :352-354

← 1 2 3 →