Studies with 2-arylhydrazononitriles: a new convenient synthesis of 2,4-disubstituted-1,2,3-triazole-5-amines

被引：28

作者：

Ghozlan, Said Ahmed Soliman ^{[1
]}

Abdelhamid, Ismail Abdelshafy ^{[1
]}

Ibrahim, Hamada Mohamed ^{[1
]}

Elnagdi, Mohamed Hilmy ^{[1
]}

机构：

[1] Cairo Univ, Fac Sci, Dept Chem, Giza, Egypt

来源：

ARKIVOC | 2006年

关键词：

hydrazononitriles; 1,2,3-triazoles; aminoisoxazoles;

D O I：

10.3998/ark.5550190.0007.f07

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new simple and efficient approach to 2,4-disubstituted 1,2,3-triazoles-5-amines from the reaction of 2-arylhydrazononitriles and hydroxylamine is described. Investigation of behavior of 3-phenyl-3oxo-2-arylhydrazonopropane nitriles has been undertaken. In addition to readily reported formation of aminoisoxazoles, 4-benzoyl-1-aryl-1,2,3-triazole-5-amines 5f,g were prepared via cyclising products of reacting 2f,g with hydroxylamine in basic medium.

引用

页码：53 / 60

页数：8

共 19 条

[1] Chemical reactivity of [1,2,3]triazolo[1,5-a]- and [1,5-c]-pyrimidinium salts [J].