Dynamic regulation of the microtubule and actin cytoskeleton in zebrafish epiboly

被引:15
|
作者
Lee, Shyh-Jye [1 ,2 ,3 ,4 ]
机构
[1] Natl Taiwan Univ, Dept Life Sci, Taipei 10617, Taiwan
[2] Natl Taiwan Univ, Ctr Biotechnol, Taipei 10617, Taiwan
[3] Natl Taiwan Univ, Ctr Dev Biol & Regenerat Med, Taipei 10617, Taiwan
[4] Natl Taiwan Univ, Ctr Syst Biol, Taipei 10617, Taiwan
关键词
Gastrulation; Epiboly; Microtubule; Actin; Zebrafish; GASTRULATION CELL MOVEMENTS; E-CADHERIN ENDOCYTOSIS; MIDBLASTULA TRANSITION; DESMOSOMAL CADHERINS; ENVELOPING LAYER; MATERNAL CONTROL; BCL-2; ADHESION; EMBRYOS; PHOSPHORYLATION;
D O I
10.1016/j.bbrc.2014.08.005
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Gastrulation is a key developmental stage with striking changes in morphology. Coordinated cell movements occur to bring cells to their correct positions in a timely manner. Cell movements and morphological changes are accomplished by precisely controlling dynamic changes in cytoskeletal proteins, microtubules, and actin filaments. Among those cellular movements, epiboly produces the first distinct morphological changes in teleosts. In this review, I describe epiboly and its mechanics, and the dynamic changes in microtubule networks and actin structures, mainly in zebrafish embryos. The factors regulating those cytoskeletal changes will also be discussed. (C) 2014 Elsevier Inc. All rights reserved.
引用
收藏
页码:1 / 7
页数:7
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