Objectives. To study the patient outcomes of various approaches on 14 consecutive patients who had laparoscopic adrenalectomy surgery between October 1995 and March 1997. Methods. The patients comprised 5 men and 9 women (mean age 46.2 years, range 32 to 61) with varying diagnoses. Eleven patients had Conn's syndrome, 1 had Cushing's syndrome, 1 had a nonfunctioning adrenal adenoma, and 1 had an adrenal myelolipoma. The adenomas were confirmed by hormonal assays, biochemical tests, and computed tomography (CT) imaging. Seven adenomas were sited on the right and seven were sited on the left. We used two alternative approaches: a transabdominal approach (8 patients) and a retroperitoneal approach (6 patients). Results. None of the procedures required conversion to open surgery, nor was there any procedure-related complication. Blood loss was minimal. All the lesions were benign on final histology. The mean operating time was 135 minutes (range 80 to 190). The postoperative period was without significant complications, with patients reporting minimal pain. Patients were able to achieve an early return to oral intake and preoperative activity. The postoperative hospital period ranged from I to 10 days. Conclusions. We believe laparoscopic adrenalectomy to be a viable option in the removal of benign adrenal lesions. It is a safe technique when performed by experienced practitioners and results in faster recovery. The key advantage to this technique is its minimally invasive approach and decreased hospital costs. (C) 1998, Elsevier Science Inc. All rights reserved.