Local acoustic field enhancement of single cell photoacoustic signal detection based on metamaterial structure

被引：9
作者：
Han, Jianning [1 ]
Yang, Peng [1 ]
Tang, Shuai [2 ]
机构：
[1] North Univ China, Sch Informat & Commun Engn, Taiyuan 030051, Shanxi, Peoples R China
[2] North Univ China, Sch Sci, Taiyuan 030051, Shanxi, Peoples R China
来源：
AIP ADVANCES | 2019年 / 9卷 / 09期
关键词：
HIGH-RESOLUTION; MICROSCOPY;
D O I：
10.1063/1.5121365
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
The photoacoustic signal from single cell plays an important role in medical diagnosis. Currently, the single-cell photoacoustic detection has limitations. To overcome the limits, an acoustic metamaterial model based on the acoustic waveguide theory for local enhancement of the ultrahigh frequency (UHF) acoustic signals was implemented in this study and it was applied to study the acoustic signal characteristics of individual cells. The local field enhancement effect at different frequencies and the specific mechanism of the model was evaluated in the simulation experiment. This proposing acoustic metamaterial structure of good practical value can be used in various applications for acoustic signal processing.
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页数：13
相关论文
共 25 条
[1]  
Bost W, 2009, IFMBE PROC, V22, P448
[2]  
Chang-lin D., 2018, ACTA PHYS SINICA, V67
[3]   Multispectral Optoacoustic Tomography (MSOT) of Human Breast Cancer [J].
Diot, Gael ;
Metz, Stephan ;
Noske, Aurelia ;
Liapis, Evangelos ;
Schroeder, Barbara ;
Ovsepian, Saak V. ;
Meier, Reinhard ;
Rummeny, Ernst ;
Ntziachristos, Vasilis .
CLINICAL CANCER RESEARCH, 2017, 23 (22) :6912-6922
[4]   Advances in ultrasound biomicroscopy [J].
Foster, FS ;
Pavlin, CJ ;
Harasiewicz, KA ;
Christopher, DA ;
Turnbull, DH .
ULTRASOUND IN MEDICINE AND BIOLOGY, 2000, 26 (01) :1-27
[5]   Combined photoacoustic and ultrasound biomicroscopy [J].
Harrison, Tyler ;
Ranasinghesagara, Janaka C. ;
Lu, Huihong ;
Mathewson, Kory ;
Walsh, Andrew ;
Zemp, Roger J. .
OPTICS EXPRESS, 2009, 17 (24) :22041-22046
[6]   Optical-Resolution Photoacoustic Microscopy: Auscultation of Biological Systems at the Cellular Level [J].
Hu, Song ;
Wang, Lihong V. .
BIOPHYSICAL JOURNAL, 2013, 105 (04) :841-847
[7]  
Hua-qin W., 2018, LASER OPTOELECTRONIC, P22
[8]   Performance characterization of an integrated ultrasound, photoacoustic, and thermoacoustic imaging system [J].
Ke, Haixin ;
Erpelding, Todd N. ;
Jankovic, Ladislav ;
Liu, Changjun ;
Wang, Lihong V. .
JOURNAL OF BIOMEDICAL OPTICS, 2012, 17 (05)
[9]   Deeply penetrating in vivo photoacoustic imaging using a clinical ultrasound array system [J].
Kim, Chulhong ;
Erpelding, Todd N. ;
Jankovic, Ladislav ;
Pashley, Michael D. ;
Wang, Lihong V. .
BIOMEDICAL OPTICS EXPRESS, 2010, 1 (01) :278-284
[10]   PHOTOACOUSTIC ULTRASOUND (PAUS) - RECONSTRUCTION TOMOGRAPHY [J].
KRUGER, RA ;
LIU, PY ;
FANG, YR ;
APPLEDORN, CR .
MEDICAL PHYSICS, 1995, 22 (10) :1605-1609
123