Characterization of a NIR absorbing thienyl curcumin contrast agent for photoacoustic imaging

被引:21
作者
Bellinger, Stephanie [1 ]
Hatamimoslehabadi, Maryam [2 ]
Borg, Raymond E. [1 ]
La, Jeffrey [2 ]
Catsoulis, Peter [1 ]
Mithila, Farha [1 ]
Yelleswarapu, Chandra [2 ]
Rochford, Jonathan [1 ]
机构
[1] Univ Massachusetts, Dept Chem, 100 Morrissey Blvd, Boston, MA 02125 USA
[2] Univ Massachusetts, Dept Phys, 100 Morrissey Blvd, Boston, MA 02125 USA
关键词
SEMICONDUCTING POLYMER NANOPARTICLES; THIOPHENE; DYES; LIGHT; COMPLEXES; PROBES;
D O I
10.1039/c8cc03727b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The synthesis and characterization of a bis(2-dimethylaminothien-5-yl)curcumin boron difluoride chromophore is presented. Photophysical, electrochemical and computational investigations establish the properties of its absorption in the Vis-NIR spectral range relative to established curcumin dyes. Application of this thienyl curcumin dye as a photoacoustic contrast agent is investigated against the dicarbocyanine Cy5 dye in the 675-735 nm excitation range.
引用
收藏
页码:6352 / 6355
页数:4
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