Synthesis and biological activity of some novel β-diketones containing pyrazole moiety

被引：0

作者：

Kumari, Neetu ^{[1
]}

Khandelwal, Poonam ^{[1
]}

Joshi, Y. C. ^{[2
]}

机构：

[1] Mohanlal Sukhadia Univ, Dept Chem, Udaipur 313001, Rajasthan, India

[2] Univ Rajasthan, Dept Chem, Jaipur 302004, Rajasthan, India

来源：

JOURNAL OF THE INDIAN CHEMICAL SOCIETY | 2014年 / 91卷 / 08期

关键词：

Acetophenone derivative; pyrazole-1-acetyl chloride; 1,3-diketones; sodium methoxide; antibacterial; antifungal activity; LIPID-PEROXIDATION; PHYTIC ACID; TANNIC-ACID; 1,3-DIKETONE; DERIVATIVES;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reaction of substituted pyrazole-l-acetyl chloride (3) with acetophenone derivative (4) in presence of sodium methoxide in dry toluene led to the synthesis of substituted beta-diketones containing pyrazole moiety (5a-l). All the newly synthesized compounds were confirmed by elemental analysis and IR, H-1, C-13 NMR and mass spectral studies. The compounds (5a-l) were evaluated for their antibacterial and antifungal activities.

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页码：1577 / 1582

页数：6

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