Lgr5 joins the club of gastric stem cell markers in the corpus

被引：17

作者：

Phesse, Toby J. ^{[1
]}

Sansom, Owen J. ^{[2
,3
]}

机构：

[1] Cardiff Univ, European Canc Stem Cell Res Inst, Cardiff CF24 4HQ, S Glam, Wales

[2] Canc Res UK Beatson Inst, Garscube Estate, Glasgow G61 1BD, Lanark, Scotland

[3] Univ Glasgow, Inst Canc Sci, Glasgow G61 1BD, Lanark, Scotland

来源：

NATURE CELL BIOLOGY | 2017年 / 19卷 / 07期

关键词：

EPITHELIUM; STOMACH; MICE; IDENTIFICATION;

D O I：

10.1038/ncb3567

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Several markers of gastric stem cells have been identified in recent years. Now a study demonstrates that Lgr5 marks a population of reserve stem cells located at the base of the corpus glands of the gastric epithelium, and that these cells can also act as a cell-of-origin for gastric tumorigenesis. © 2017 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.

引用

页码：752 / 754

页数：3

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