Association of delay of urgent or emergency surgery with mortality and use of health care resources: a propensity score-matched observational cohort study

被引:106
作者
McIsaac, Daniel I. [1 ,4 ,5 ]
Abdulla, Karim [1 ]
Yang, Homer [1 ,4 ]
Sundaresan, Sudhir [2 ,4 ]
Doering, Paula [4 ]
Vaswani, Sandeep Green [6 ]
Thavorn, Kednapa [5 ]
Forster, Alan J. [3 ,4 ,5 ]
机构
[1] Univ Ottawa, Dept Anesthesiol, Ottawa, ON, Canada
[2] Univ Ottawa, Dept Surg, Ottawa, ON, Canada
[3] Univ Ottawa, Dept Med, Ottawa, ON, Canada
[4] Ottawa Hosp, Civ Campus, Ottawa, ON, Canada
[5] Ottawa Hosp, Res Inst, Ottawa, ON, Canada
[6] Inst Healthcare Optimizat, Newton, MA USA
关键词
SURGICAL DELAY; OPERATING-ROOM; CRITICAL DETERMINANT; ELDERLY-PATIENTS; GENERAL-SURGERY; RISK; SURVIVAL; INPATIENT; OUTCOMES;
D O I
10.1503/cmaj.160576
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BACKGROUND: Delay of surgery for hip fracture is associated with increased risk of morbidity and mortality, but the effects of surgical delays on mortality and resource use in the context of other emergency surgeries is poorly described. Our objective was to measure the independent association between delay of emergency surgery and in-hospital mortality, length of stay and costs. METHODS: We identified all adult patients who underwent emergency noncardiac surgery between January 2012 and October 2014 at a single tertiary care centre. Delay of surgery was defined as the time from surgical booking to operating room entry exceeding institutionally defined acceptable wait times, based on a standardized 5-level priority system that accounted for surgery type and indication. Patients with delayed surgery were matched to those without delay using propensity scores derived from variables that accounted for details of admission and the hospital stay, patient characteristics, physiologic instability, and surgical urgency and risk. RESULTS: Of 15 160 patients, 2820 (18.6%) experienced a delay. The mortality rates were 4.9% (138/2820) for those with delay and 3.2% (391/12 340) for those without delay (odds ratio [OR] 1.59, 95% confidence interval [CI] 1.30-1.93). Within the propensity-matched cohort, delay was significantly associated with mortality (OR 1.56, 95% CI 1.18-2.06), increased length of stay (incident rate ratio 1.07, 95% CI 1.01-1.11) and higher total costs (incident rate ratio 1.06, 95% CI 1.01-1.11). INTERPRETATION: Delayed operating room access for emergency surgery was associated with increased risk of inhospital mortality, longer length of stay and higher costs. System issues appeared to underlie most delays and must be addressed to improve the outcomes of emergency surgery.
引用
收藏
页码:E905 / E912
页数:8
相关论文
共 33 条
[1]   Reporting of covariate selection and balance assessment in propensity score analysis is suboptimal: a systematic review [J].
Ali, M. Sanni ;
Groenwold, Rolf H. H. ;
Belitser, Svetlana V. ;
Pestman, Wiebe R. ;
Hoes, Arno W. ;
Roes, Kit C. B. ;
de Boer, Anthonius ;
Klungel, Olaf H. .
JOURNAL OF CLINICAL EPIDEMIOLOGY, 2015, 68 (02) :122-131
[2]   Allocating operating room resources to an acute care surgery service does not affect wait-times for elective cancer surgeries: a retrospective cohort study [J].
Anantha, Ram Venkatesh ;
Paskar, Dave ;
Vogt, Kelly ;
Crawford, Silvie ;
Parry, Neil ;
Leslie, Ken .
WORLD JOURNAL OF EMERGENCY SURGERY, 2014, 9
[3]  
[Anonymous], 2007, HLTH IND 2007
[4]  
Austin PC, 2008, STAT MED, V27, P2037, DOI 10.1002/sim.3150
[5]   A Tutorial on Methods to Estimating Clinically and Policy-Meaningful Measures of Treatment Effects in Prospective Observational Studies: A Review [J].
Austin, Peter C. ;
Laupacis, Andreas .
INTERNATIONAL JOURNAL OF BIOSTATISTICS, 2011, 7 (01)
[6]   Using the Standardized Difference to Compare the Prevalence of a Binary Variable Between Two Groups in Observational Research [J].
Austin, Peter C. .
COMMUNICATIONS IN STATISTICS-SIMULATION AND COMPUTATION, 2009, 38 (06) :1228-1234
[7]   Time from admission to initiation of surgery for source control is a critical determinant of survival in patients with gastrointestinal perforation with associated septic shock [J].
Azuhata, Takeo ;
Kinoshita, Kosaku ;
Kawano, Daisuke ;
Komatsu, Tomonori ;
Sakurai, Atsushi ;
Chiba, Yasutaka ;
Tanjho, Katsuhisa .
CRITICAL CARE, 2014, 18 (03)
[8]   Development and Evaluation of the Universal ACS NSQIP Surgical Risk Calculator: A Decision Aid and Informed Consent Tool for Patients and Surgeons [J].
Bilimoria, Karl Y. ;
Liu, Yaoming ;
Paruch, Jennifer L. ;
Zhou, Lynn ;
Kmiecik, Thomas E. ;
Ko, Clifford Y. ;
Cohen, Mark E. .
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2013, 217 (05) :833-+
[9]   Surgical delay is a critical determinant of survival in perforated peptic ulcer [J].
Buck, D. L. ;
Vester-Andersen, M. ;
Moller, M. H. .
BRITISH JOURNAL OF SURGERY, 2013, 100 (08) :1045-1048
[10]   Accelerated care versus standard care among patients with hip fracture: the HIP ATTACK pilot trial [J].
Buse, Giovanna Lurati ;
Bhandari, Mohit ;
Sancheti, Parag ;
Rocha, Steve ;
Winemaker, Mitchell ;
Adili, Anthony ;
de Beer, Justin ;
Tiboni, Maria ;
Neary, John D. D. ;
Dunlop, Valerie ;
Gauthier, Leslie ;
Patel, Ameen ;
Robinson, Andrea ;
Rodseth, Reitze N. ;
Kolesar, Rick ;
Farrell, Janet ;
Crowther, Mark ;
Tandon, Vikas ;
Magloire, Patrick ;
Dokainish, Hisham ;
Joseph, Philip ;
Tomlinson, Charles W. ;
Salehian, Omid ;
Hastings, Debbie ;
Hunt, Dereck L. ;
Van Spall, Harriette ;
Cosman, Tammy L. ;
Simpson, Diane L. ;
Cowan, David ;
Guyatt, Gordon ;
Alvarado, Kim ;
Evans, W. K. ;
Mizera, Ryszard ;
Eikelboom, John ;
Cook, Deborah ;
Loeb, Mark ;
Johnstone, Jennie ;
Kearon, Clive ;
Sessler, Daniel I. ;
VanHelder, Thomas ;
Rao-Melacini, Purnima ;
Worster, Andrew ;
Patil, Atul ;
McLean, Richard ;
Macdonald, Anne-Marie ;
Badzioch, Rick ;
Devereaux, P. J. .
CANADIAN MEDICAL ASSOCIATION JOURNAL, 2014, 186 (01) :E52-E60