Donation after circulatory death donors in highrisk recipients undergoing bilateral lung transplantation: An ISHLT database registry analysis

被引：3

作者：

Reck dos Santos, Pedro Augusto ^{[1
,2
]}

Zimermann Teixeira, Paulo Jose ^{[2
,3
]}

Neto, Daniel Messias de Moraes ^{[4
]}

Langlais, Blake ^{[5
]}

Cypel, Marcelo ^{[6
]}

机构：

[1] Mayo Clin, Dept Cardiothorac Surg, Phoenix, AZ USA

[2] Univ Fed Ciencias Saude Porto Alegre, Programa Posgrad Ciencias Saude, Porto Alegre, RS, Brazil

[3] Univ Fed Ciencias Saude Porto Alegre, Dept Internal Med, Respirol, Porto Alegre, RS, Brazil

[4] Stanford Univ, Dept Cardiothorac Surg, Stanford, CA 94305 USA

[5] Mayo Clin, Dept Quantitat Hlth Sci, Scottsdale, AZ USA

[6] Univ Hlth Network, Univ Toronto, Div Thorac Surg, Toronto, ON, Canada

来源：

JOURNAL OF HEART AND LUNG TRANSPLANTATION | 2022年 / 41卷 / 06期

关键词：

lung transplantation; end-stage lung diseases; donation after circulatory death; brain dead donation;

D O I：

10.1016/j.healun.2022.02.009

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Lung transplantation (LTx) using donation after circulatory death (DCD) donors has demonstrated equivalent outcomes compared to donation after brain dead (DBD) donors. However, data from the use of DCDs for high-risk (HR) recipients is limited. We performed a propensity match study to evaluate the impact of DCD transplantation on HR recipients. In addition, we assessed the effect of recipient profile (HR vs. non-HR) in DCDs and DBDs LTx. From 2009-2018, 1829 double lung transplants (DLTx) for HR recipients were identified. Of these, 131 were performed using DCD donors. There was no difference in survival between DCDs and DBDs among HR-DLTx recipients (p = 0.16). However, HR recipients had worse survival compared to nonHR recipients in DBD (p < 0.001) but not in DCD transplantation (p = 0.95). Our findings support that DCD lungs are appropriate for HR recipients and should not be considered inferior or higher-risk donors. Its use should be further stimulated rather than restricted. J Heart Lung Transplant 2022;41:712- 715 (c) 2022 International Society for Heart and Lung Transplantation. All rights reserved.

引用

页码：712 / 715

页数：4

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