Endoscopic Treatment of Hypothalamic Hamartomas

被引:8
作者
Shim, Kyu Won [1 ]
Park, Eun Kyung [1 ]
Kim, Dong-Seok [1 ]
机构
[1] Yonsei Univ, Coll Med, Brain Korea Project Med Sci 21, Dept Pediat Neurosurg,Severance Childrens Hosp, Seoul 03722, South Korea
关键词
Hypothalamic hamartoma; Epilepsy; Endoscope; GELASTIC EPILEPSY; REFRACTORY EPILEPSY; SURGICAL-TREATMENT; SEIZURES; SURGERY; STIMULATION; RESECTION; EEG; LAUGHTER; NETWORK;
D O I
10.3340/jkns.2017.0101.005
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Hypothalamic hamartoma (HH) is a benign indolent lesion despite the presentation of refractory epilepsy. Behavioral disturbances and endocrine problems are additional critical symptoms that arise along with HHs. Due to its nature of generating epileptiform discharge and spreading to cortical region, various management strategies have been proposed and combined. Surgical approaches with open craniotomy or endoscopy, stereotactic approaches with radiosurgery and gamma knife surgery or radiofrequency thermos-coagulation, and laser ablation have been introduced. Topographical dimension and the surgeon's preference are key factors for treatment modalities. Endoscopic disconnection has been one of the most favorable options performed in treating HHs. Here we discuss presurgical evaluation, patient selection, surgical procedures, and complications.
引用
收藏
页码:294 / 300
页数:7
相关论文
共 40 条
[1]   The relationship between magnetic resonance imaging findings and clinical manifestations of hypothalamic hamartoma [J].
Arita, K ;
Ikawa, F ;
Kurisu, K ;
Sumida, M ;
Harada, K ;
Uozumi, T ;
Monden, S ;
Yoshida, J ;
Nishi, Y .
JOURNAL OF NEUROSURGERY, 1999, 91 (02) :212-220
[2]   Ictal laughter associated with paroxysmal hypothalamopituitary dysfunction [J].
Arroyo, S ;
Santamaria, J ;
Lomena, F ;
Catafau, A ;
Casamitjana, R ;
Setoain, J ;
Tolosa, E .
EPILEPSIA, 1997, 38 (01) :114-117
[3]   Hypothalamic hamartomas associated with epilepsy: Ultrastructural features [J].
Beggs, John ;
Nakada, Satoko ;
Fenoglio, Kristina ;
Wu, Jie ;
Coons, Stephen ;
Kerrigan, John F. .
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2008, 67 (07) :657-668
[4]   Hypothalamic hamartoma and seizures: A treatable epileptic encephalopathy [J].
Berkovic, SF ;
Arzimanoglou, A ;
Kuzniecky, R ;
Harvey, AS ;
Palmini, A ;
Andermann, F .
EPILEPSIA, 2003, 44 (07) :969-973
[5]  
BOYKO OB, 1991, AM J NEURORADIOL, V12, P309
[6]   Autonomic and hormonal ictal changes in gelastic seizures from hypothalamic hamartomas [J].
Cerullo, A ;
Tinuper, P ;
Provini, F ;
Contin, M ;
Rosati, A ;
Marini, C ;
Cortelli, P .
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1998, 107 (05) :317-322
[7]   Endoscopic disconnection for hypothalamic hamartoma with intractable seizure - Report of four cases [J].
Choi, JU ;
Yang, KH ;
Kim, TG ;
Chang, JH ;
Chang, JW ;
Lee, BI ;
Kim, DS .
JOURNAL OF NEUROSURGERY, 2004, 100 (05) :506-511
[8]  
Choi JU, 2012, ADV TECHNICAL STANDA, V39, P118
[9]   The histopathology of hypothalamic hamartomas: Study of 57 cases [J].
Coons, Stephen W. ;
Rekate, Harold L. ;
Prenger, Erin C. ;
Wang, Norman ;
Drees, Cornelia ;
Ng, Yu-tze ;
Chung, Steven S. ;
Kerrigan, John F. .
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2007, 66 (02) :131-141
[10]   Disconnecting surgical treatment of hypothalamic hamartoma in children and adults with refractory epilepsy and proposal of a new classification [J].
Delalande, O ;
Fohlen, M .
NEUROLOGIA MEDICO-CHIRURGICA, 2003, 43 (02) :61-68