Catalyst-free highly regio- and stereoselective ring opening of epoxides and aziridines with sodium azide using poly(ethylene glycol) as an efficient reaction medium

被引：30

作者：

Das, Biswanath ^{[1
]}

Reddy, Vtukuri Saidi ^{[1
]}

Tehseen, Fouzia ^{[1
]}

Krishnaiah, Maddeboina ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Organ Chem Div 1, Hyderabad 500007, Andhra Pradesh, India

来源：

SYNTHESIS-STUTTGART | 2007年 / 05期

关键词：

epoxide; aziridine; PEG-400; 2-azido alcohol; 2-azido amine;

D O I：

10.1055/s-2007-965921

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ring opening of epoxides and aziridines has readily been carried out at room temperature using poly(ethylene glycol) (PEG400) as the efficient reaction medium to form the corresponding 2-azido alcohols and 2-azido amines, respectively in excellent yields (95-99%) within 30-45 minutes and with high regio- and streoselectivity.

引用

页码：666 / 668

页数：3

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