Catalyst-free highly regio- and stereoselective ring opening of epoxides and aziridines with sodium azide using poly(ethylene glycol) as an efficient reaction medium

被引：30

作者：

Das, Biswanath ^{[1
]}

Reddy, Vtukuri Saidi ^{[1
]}

Tehseen, Fouzia ^{[1
]}

Krishnaiah, Maddeboina ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Organ Chem Div 1, Hyderabad 500007, Andhra Pradesh, India

来源：

SYNTHESIS-STUTTGART | 2007年 / 05期

关键词：

epoxide; aziridine; PEG-400; 2-azido alcohol; 2-azido amine;

D O I：

10.1055/s-2007-965921

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ring opening of epoxides and aziridines has readily been carried out at room temperature using poly(ethylene glycol) (PEG400) as the efficient reaction medium to form the corresponding 2-azido alcohols and 2-azido amines, respectively in excellent yields (95-99%) within 30-45 minutes and with high regio- and streoselectivity.

引用

页码：666 / 668

页数：3

共 4 条

[1] Highly regio- and stereoselective ring-opening of epoxides and aziridines with sodium azide using ammonium-12-molybdophosphate
Das, Biswanath
Reddy, Vtukuri Saidi
Krishnaiah, Maddeboina
Rao, Yerra Koteswara
JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 2007, 270 (1-2) : 89 - 92
[2] Studies on novel synthetic methodologies. Part 122. An efficient catalyst-free regio- and stereoselective ring-opening of epoxides with phenoxides using polyethylene glycol as the reaction medium
Das, Biswanath
Krishnalah, Maddeboina
Thirupathi, Ponnaboina
Laxminarayana, Keetha
TETRAHEDRON LETTERS, 2007, 48 (24) : 4263 - 4265
[3] Efficient regio- and stereo-selective cleavage of aziridines and epoxides using an ionic liquid as reagent and reaction medium
Ranu, Brindaban C.
Adak, Laksmikanta
Banerjee, Subhash
CANADIAN JOURNAL OF CHEMISTRY, 2007, 85 (05) : 366 - 371
[4] An efficient catalyst-free synthesis of thiiranes from oxiranes using polyethylene glycol as the reaction medium
Das, Biswanath
Reddy, V. Saidi
Krishnaiah, M.
TETRAHEDRON LETTERS, 2006, 47 (48) : 8471 - 8473

← 1 →