Synthesis of cyclopropa[c]indeno[1,2-b]quinolines through a MCR/Staudinger/aza-Wittig sequence

被引：6
|
作者：
Nie, Bing-Jie [1 ]
Wu, Li-Hui [1 ]
Hu, Ruo-Fei [1 ]
Sun, Yang [1 ]
Wu, Jing [1 ]
He, Ping [1 ]
Huang, Nian-Yu [2 ]
机构：
[1] Hubei Univ Arts & Sci, Coll Chem Engn & Food Sci, Xiangyang 441053, Hubei, Peoples R China
[2] China Three Gorges Univ, Coll Biol & Pharmaceut Sci, Hubei Key Lab Nat Prod Res & Dev, Yichang, Hubei, Peoples R China
来源：
SYNTHETIC COMMUNICATIONS | 2017年 / 47卷 / 15期
基金：
中国国家自然科学基金;
关键词：
Cyclopropa[c]indeno[1; 2-b]quinolines; multicomponent reaction; spirocyclopropane; Staudinger; aza-Wittig reaction; HIGHLY STEREOSELECTIVE-SYNTHESIS; MULTICOMPONENT REACTIONS; ONE-POT; CYCLOPROPANES; CONSTRUCTION; DERIVATIVES; CHEMISTRY; BIOLOGY; DESIGN; ACIDS;
D O I：
10.1080/00397911.2017.1328065
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Spirocyclopropanes were prepared from aromatic aldehydes, 1,3-indandione and acetophenones through a halogenation/S(N)2-displacement/Michael-initiated ring-closing sequence by a pyridinium-ylide-assisted multicomponent reaction, and their further use was also researched in the construction of cyclopropa[c]indeno[1,2-b]quinolines through subsequent Staudinger/aza-Wittig reactions.
引用
收藏
页码：1368 / 1374
页数：7
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