Porous bioactive glass microspheres prepared by flame synthesis process

被引:27
作者
Kraxner, Jozef [1 ]
Michalek, Martin [1 ]
Romero, Acacio Rincon [2 ]
Elsayed, Hamada [2 ,3 ]
Bernardo, Enrico [2 ]
Boccaccini, Aldo R. [4 ]
Galusek, Dusan [5 ,6 ]
机构
[1] Alexander Dubcek Univ Trencin, FunGlass, Trencin, Slovakia
[2] Univ Padua, Dept Ind Engn, Padua, Italy
[3] Natl Res Ctr, Ceram Dept, Cairo, Egypt
[4] Univ Erlangen Nurnberg, Inst Biomat, Dept Mat Sci & Engn, D-91058 Erlangen, Germany
[5] Alexander Dubcek Univ Trencin, Joint Glass Ctr, IIC SAS, TnUAD, Trencin, Slovakia
[6] Alexander Dubcek Univ Trencin, FChFT STU, FunGlass, Trencin, Slovakia
基金
欧盟地平线“2020”;
关键词
Bioactive glass; Porous microspheres; Alkaline activation; Flame synthesis;
D O I
10.1016/j.matlet.2019.126625
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
A scaleable, low cost processing method to prepare porous bioactive glass (BG) microspheres is presented. Glass powder with composition based on 45S5 BG and exhibiting irregularly shaped particles was fabricated by conventional melting. Glass powder was alkali activated to induce pore formation during the following flame synthesis step. Porous microspheres, with diameters ranging between 45 and 75 mu m, were successfully prepared and characterized by X-ray diffraction, Fourier-transform infrared spectroscopy, and scanning electron microscopy with energy-dispersive X-ray spectroscopy. The porous bioactive glass microspheres are promising candidates for applications in bone regeneration, tissue engineering, and as carriers for controlled drug delivery. (C) 2019 Elsevier B.V. All rights reserved.
引用
收藏
页数:4
相关论文
共 12 条
[1]   Fabrication and characterization of sol-gel derived 45S5 Bioglass®-ceramic scaffolds [J].
Chen, Qi-Zhi ;
Thouas, George A. .
ACTA BIOMATERIALIA, 2011, 7 (10) :3616-3626
[2]  
Hench L.L., 1971, Journal of Biomedical Materials Research Symposium, V36, P117, DOI [DOI 10.1002/JBM.820050611, 10.1002/jbm.820050611]
[3]   A review of the biological response to ionic dissolution products from bioactive glasses and glass-ceramics [J].
Hoppe, Alexander ;
Gueldal, Nusret S. ;
Boccaccini, Aldo R. .
BIOMATERIALS, 2011, 32 (11) :2757-2774
[4]   Porous calcium phosphate glass microspheres for orthobiologic applications [J].
Hossain, Kazi M. Zakir ;
Patel, Uresha ;
Kennedy, Andrew R. ;
Macri-Pellizzeri, Laura ;
Sottile, Virginie ;
Grant, David M. ;
Scammell, Brigitte E. ;
Ahmed, Ifty .
ACTA BIOMATERIALIA, 2018, 72 :396-406
[5]   Development of microspheres for biomedical applications: A review [J].
Hossain K.M.Z. ;
Patel U. ;
Ahmed I. .
Progress in Biomaterials, 2015, 4 (1) :1-19
[6]   Reprint of: Review of bioactive glass: From Hench to hybrids [J].
Jones, Julian R. .
Acta Biomaterialia, 2015, 23 (0S) :S53-S82
[7]   Porous-wall hollow glass microspheres as novel potential nanocarriers for biomedical applications [J].
Li, Shuyi ;
Nguyen, Lynsa ;
Xiong, Hairong ;
Wang, Meiyao ;
Hu, Tom C. -C. ;
She, Jin-Xiong ;
Serkiz, Steven M. ;
Wicks, George G. ;
Dynan, William S. .
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2010, 6 (01) :127-136
[8]   Porous glass-ceramics from alkali activation and sinter-crystallization of mixtures of waste glass and residues from plasma processing of municipal solid waste [J].
Monich, Patricia Rabelo ;
Romero, Acacio Rincon ;
Hoellen, Daniel ;
Bernardo, Enrico .
JOURNAL OF CLEANER PRODUCTION, 2018, 188 :871-878
[9]  
Reddy P.M., 2014, SCI ENG COMPOS MATER, V23, DOI [10.1515/secm2014-0057, DOI 10.1515/SECM2014-0057]
[10]   Novel 'inorganic gel casting' process for the manufacturing of glass foams [J].
Rincon, Acacio ;
Giacomello, Giovanni ;
Pasetto, Marco ;
Bernardo, Enrico .
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY, 2017, 37 (05) :2227-2234