Enantioselective synthesis of α-methyl-D-cysteine and lanthionine building blocks via α-methyl-D-serine-β-lactone

被引：62

作者：

Smith, ND ^{[1
]}

Goodman, M ^{[1
]}

机构：

[1] Univ Calif San Diego, Dept Chem & Biochem, La Jolla, CA 92093 USA

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 07期

关键词：

D O I：

10.1021/ol034025p

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] We report here the enantioselective synthesis of Boc-alpha-methyl-D-cysteine(PMB)-OH and lanthionine building blocks through the regloselective ring opening of key intermediate Boc-alpha-methyl-D-serine-beta-lactone.

引用

页码：1035 / 1037

页数：3

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