Approach to the Solid Organ Transplant Patient with Suspected Fungal Infection

被引：27

作者：

Anesi, Judith A. ^{[1
]}

Baddley, John W. ^{[2
,3
]}

机构：

[1] Univ Penn, Div Infect Dis, 3400 Spruce St,3 Silverstein,Suite E, Philadelphia, PA 19104 USA

[2] Univ Alabama Birmingham, Dept Med, 1900 Univ Blvd,229 THT, Birmingham, AL 35294 USA

[3] Birmingham VA Med Ctr, Med Serv, 700 South 19th St, Birmingham, AL 35233 USA

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 2016年 / 30卷 / 01期

关键词：

Solid organ transplant; Invasive fungal infection; Candida; Aspergillus; Endemic fungi; Cryptococcus; Mold; PNEUMOCYSTIS-CARINII-PNEUMONIA; PRIMARY CUTANEOUS CRYPTOCOCCOSIS; CENTRAL-NERVOUS-SYSTEM; BETA-D-GLUCAN; INVASIVE-ASPERGILLOSIS; RISK-FACTORS; CLINICAL-MANIFESTATIONS; PULMONARY ASPERGILLOSIS; ANTIFUNGAL PROPHYLAXIS; LIVER-TRANSPLANTATION;

D O I：

10.1016/j.idc.2015.10.001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In solid organ transplant (SOT) recipients, invasive fungal infections (IFIs) are associated with significant morbidity and mortality. Detection of IFIs can be difficult because the signs and symptoms are similar to those of viral or bacterial infections, and diagnostic techniques have limited sensitivity and specificity. Clinicians must rely on knowledge of the patient's risk factors for fungal infection to make a diagnosis. The authors describe their approach to the SOT recipient with suspected fungal infection. The epidemiology of IFIs in the SOT population is reviewed, and a syndromic approach to suspected IFI in SOT recipients is described.

引用

页码：277 / +

页数：21

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