Synthesis of indazole-N-oxides via the 1,7-electrocyclization of azomethine ylides

被引：23
作者：
Nyerges, M
Virányi, A
Zhang, WM
Groundwater, PW
Blaskó, G
Toke, L
机构：
[1] Tech Univ Budapest, Hungarian Acad Sci, Res Grp, Dept Organ Chem Technol, H-1521 Budapest, Hungary
[2] Univ Sunderland, Sunderland Pharm Sch Drug Design & Mol Modelling, Sunderland SR1 3SD, England
[3] EGIS Pharmaceut Ltd, H-1475 Budapest, Hungary
来源：
TETRAHEDRON | 2004年 / 60卷 / 44期
基金：
匈牙利科学研究基金会;
关键词：
cycloadditions; electrocyclic reactions; indazoles; isoquinolines; nitro compounds;
D O I：
10.1016/j.tet.2004.08.026
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The first examples of the 1,7-electrocyclization of azomethine ylides onto a nitro group, to give benz-1,2,6-oxadiazepine intermediates are reported. Subsequent ring contraction results in the formation of indazole-N-oxides. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码：9937 / 9944
页数：8
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