Synthesis of indazole-N-oxides via the 1,7-electrocyclization of azomethine ylides

被引：23

作者：

Nyerges, M

Virányi, A

Zhang, WM

Groundwater, PW

Blaskó, G

Toke, L

机构：

[1] Tech Univ Budapest, Hungarian Acad Sci, Res Grp, Dept Organ Chem Technol, H-1521 Budapest, Hungary

[2] Univ Sunderland, Sunderland Pharm Sch Drug Design & Mol Modelling, Sunderland SR1 3SD, England

[3] EGIS Pharmaceut Ltd, H-1475 Budapest, Hungary

来源：

TETRAHEDRON | 2004年 / 60卷 / 44期

基金：

匈牙利科学研究基金会;

关键词：

cycloadditions; electrocyclic reactions; indazoles; isoquinolines; nitro compounds;

D O I：

10.1016/j.tet.2004.08.026

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first examples of the 1,7-electrocyclization of azomethine ylides onto a nitro group, to give benz-1,2,6-oxadiazepine intermediates are reported. Subsequent ring contraction results in the formation of indazole-N-oxides. (C) 2004 Elsevier Ltd. All rights reserved.

引用

收藏

页码：9937 / 9944

页数：8

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