An olfactory sensory map in the fly brain

被引：816

作者：

Vosshall, LB ^{[1
]}

Wong, AM ^{[1
]}

Axel, R ^{[1
]}

机构：

[1] Columbia Univ Coll Phys & Surg, Howard Hughes Med Inst, Dept Biochem & Mol Biophys, New York, NY 10032 USA

来源：

CELL | 2000年 / 102卷 / 02期

关键词：

D O I：

10.1016/S0092-8674(00)00021-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have isolated the "complete" repertoire of genes encoding the odorant receptors in Drosophila and employ these genes to provide a molecular description of the organization of the peripheral olfactory system. The repertoire of Drosophila odorant receptors is encoded by 57 genes. Individual sensory neurons are likely to express only a single receptor gene. Neurons expressing a given gene project axons to one or two spatially invariant glomeruli in the antennal robe. The insect brain therefore retains a two-dimensional map of receptor activation such that the quality of an odor may be encoded by different spatial patterns of activity in the antennal lobe.

引用

页码：147 / 159

页数：13

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