An introduction to electrochemical DNA biosensors

被引:208
作者
Odenthal, Katherine J. [1 ]
Gooding, J. Justin [1 ]
机构
[1] Univ New S Wales, Sch Chem, Sydney, NSW 2052, Australia
关键词
D O I
10.1039/b701816a
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Electrochemical DNA biosensors exploit the affinity of single-stranded DNA for complementary strands of DNA and are used in the detection of specific sequences of DNA with a view towards developing portable analytical devices. Great progress has been made in this field but there are still numerous challenges to overcome. This review for researchers new to the field describes the components of electrochemical DNA biosensors and the important issues in their design. Methods of transducing DNA binding events are discussed along with future directions for DNA biosensors.
引用
收藏
页码:603 / 610
页数:8
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