RECK Expression in the Rat Ventral Prostate: Response to Castration Involves a Balance Between Epithelial and Stromal Expression

被引：6

作者：

Peters, Helene ^{[1
]}

Augusto, Taize Machado ^{[1
]}

Bruni-Cardoso, Alexandre ^{[1
]}

Carvalho, Hernandes F. ^{[1
]}

机构：

[1] State Univ Campinas UNICAMP, Inst Biol, Dept Anat Cell Biol Physiol & Biophys, BR-13083863 Campinas, SP, Brazil

来源：

ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY | 2010年 / 293卷 / 06期

关键词：

castration; prostate; in situ hybridization; RECK; APOPTOSIS; GLAND; INHIBITOR; SYSTEM; CANCER; MMP-9;

D O I：

10.1002/ar.21140

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

RECK is expressed in the rat ventral prostate. The amount of mRNA increased after castration In, situ hybridization and immunohistochemistry demonstrated a transition from epithelial to stromal expression This demonstrates that stromal cells upregulate RECK expression to regulate matrix metalloproteinases activity responsible for extracellular matrix (ECM) changes occurring after castration Anat Rec, 293.993-997, 2010. (C) 2010 Wiley-Liss, Inc

引用

页码：993 / 997

页数：5

共 26 条

[1]

Antonioli E, 2004, J ANDROL, V25, P50

[2] Effects of long-term castration on the smooth muscle cell phenotype of the rat ventral prostate [J].

Antonioli, Eliane ;

Cardoso, Alexandre Bruni ;

Carvalho, Hernandes F. .

JOURNAL OF ANDROLOGY, 2007, 28 (05) :777-783

[3] Remodeling of rat ventral prostate after castration involves heparanase-1 [J].

Augusto, Taize M. ;

Felisbino, Sergio L. ;

Carvalho, Hernandes F. .

CELL AND TISSUE RESEARCH, 2008, 332 (02) :307-315

[4] Localized matrix metalloproteinase (MMP)-2 and MMP-9 activity in the rat ventral prostate during the first week of postnatal development [J].

Bruni-Cardoso, Alexandre ;

Vilamaior, Patricia S. L. ;

Taboga, Sebastiao R. ;

Carvalho, Hernandes F. .

HISTOCHEMISTRY AND CELL BIOLOGY, 2008, 129 (06) :805-815

[5]

BRUNICARDOSO A, 2009, INT J ANDROL, P1365

[6]

Carvalho Hernandes Faustino De, 1996, Cell Biology International, V20, P809

[7]

DAVIES G, 2001, CLIN CANCER RES, V1, P34

[8] Tissue inhibitor of metalloproteinase-2 (TIMP-2) location in the ventral, lateral, dorsal and anterior lobes of rat prostate by immunohistochemistry [J].

Delella, Flavia K. ;

Justulin, Luis A., Jr. ;

Felisbino, Sergio L. .

CELL BIOLOGY INTERNATIONAL, 2007, 31 (03) :229-234

[9] Gene expression profiling identifies a unique androgen-mediated inflammatory/immune signature and a PTEN (phosphatase and tensin homolog deleted on chromosome 10)-mediated apoptotic response specific to the rat ventral prostate [J].

Desai, KV ;

Michalowska, AM ;

Kondaiah, P ;

Ward, JM ;

Shih, JH ;

Green, JE .

MOLECULAR ENDOCRINOLOGY, 2004, 18 (12) :2895-2907

[10]

EMSON PC, 1992, SITU HYBRIDIZATION P, P45

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