Innovative method for prioritizing emerging disinfection by-products (DBPs) in drinking water on the basis of their potential impact on public health

被引：136

作者：

Hebert, Armelle ^{[1
]}

Forestier, Delphine

Lenes, Dorothee ^{[2
]}

Benanou, David ^{[2
]}

Jacob, Severine ^{[3
]}

Arfi, Catherine ^{[4
]}

Lambolez, Lucie

Levi, Yves ^{[5
]}

机构：

[1] Veolia Environm Rech & Innovat, Pole Evaluat & Veille Sanit, Hlth Assessment & Surveillance Dept, F-92500 Rueil Malmaison, France

[2] Veolia Environm, Water Res Ctr, F-78600 Maisons Laffitte, France

[3] Veolia Water, Tech Direct, F-94410 St Maurice, France

[4] Catherine Arfi, F-92130 Issy Les Moulineaux, France

[5] Univ Paris Sud 11, Fac Pharm, Lab Sante Publ Environm, F-92296 Chatenay Malabry, France

来源：

WATER RESEARCH | 2010年 / 44卷 / 10期

关键词：

Emerging hazards; Emerging disinfection by-products; Drinking water; Safety; Prioritization; Toxicity; Health risk assessment; Chemical risk; MAMMALIAN-CELL CYTOTOXICITY; EXPOSURE ASSESSMENT; CHLORINATION; ASSOCIATION; RISK; NDMA; GENOTOXICITY; DEFECTS; CANCER;

D O I：

10.1016/j.watres.2010.02.004

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Providing microbiologically safe drinking water is a major public health issue. However, chemical disinfection can produce unintended health hazards involving disinfection by-products (DBPs). In an attempt to clarify the potential public health concerns associated with emerging disinfection by-products (EDBPs), this study was intended to help to identify those suspected of posing potential related health effects. In view of the ever-growing list of EDBPs in drinking water and the lack of consensus about them, we have developed an innovative prioritization method that would allow us to address this issue. We first set up an exhaustive database including all the current published data relating to EDBPs in drinking water (toxicity, occurrence, epidemiology and international or local guidelines/regulations). We then developed a ranking method intended to prioritize the EDBPs. This method, which was based on a calculation matrix with different coefficients, was applied to the data regarding their potential contribution to the health risk assessment process. This procedure allowed us to identify and rank three different groups of EDBPs: Group I, consisting of the most critical EDBPs with regard to their potential health effects, has moderate occurrence but the highest toxicity. Group II has moderate to elevated occurrence and is associated with relevant toxicity, and Group III has very low occurrence and unknown or little toxicity. The EDBPs identified as posing the greatest potential risk using this method were as follows: NDMA and other nitrosamines, MX and other halofuranones, chlorate, formaldehyde and acetaldehyde, 2,4,6-trichlorophenol and pentachlorophenol, hydrazine, and two unregulated halomethanes, dichloromethane and tetrachloromethane. Our approach allowed us to define the EDBPs that it is most important to monitor in order to assess population exposure and related public health issues, and thus to improve drinking water treatment and distribution. It is also important to extend our knowledge about exposure to mixtures of emerging DBPs and possible related health effects. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：3147 / 3165

页数：19