Balance Between the Proinflammatory and Anti-Inflammatory Immune Responses with Blood Transfusion in Sepsis

被引：19

作者：

Rice, Teresa C. ^{[1
]}

Pugh, Amanda M. ^{[1
]}

Caldwell, Charles C. ^{[1
]}

Schneider, Barbara St Pierre ^{[2
]}

机构：

[1] Univ Cincinnati, Coll Med, Dept Surg, Div Res, Cincinnati, OH 45267 USA

[2] Univ Nevada, Sch Nursing, Tony & Renee Marlon Angel Network Professorship, 4505 South Maryland Pkwy,Box 453018, Las Vegas, NV 89154 USA

来源：

CRITICAL CARE NURSING CLINICS OF NORTH AMERICA | 2017年 / 29卷 / 03期

关键词：

Leukocyte reduction; Immunosuppression; Cytokines; Sepsis; Inflammation; Blood transfusion; CRITICALLY-ILL; CYTOKINE PRODUCTION; CLINICAL-OUTCOMES; ROUTINE STORAGE; CELL UNITS; IMMUNOSUPPRESSION; INFECTION; SURGERY; MICROPARTICLES; ANEMIA;

D O I：

10.1016/j.cnc.2017.04.003

中图分类号：

R47 [护理学];

学科分类号：

1011 ;

摘要：

Blood product transfusion may exacerbate the initial immunosuppressive response of sepsis. Nurses and other patient care providers must be diligent in recognizing and managing a worsening immune status, using flow cytometry to monitor patients' immune status. This type of monitoring may be instrumental in reducing morbidity and mortality in persons with sepsis. This article discusses the recent literature on the associated inflammatory responses that occur with blood transfusion and provides an analysis of alterations in key inflammatory pathways in response to transfusion in a sepsis population.

引用

页码：331 / +

页数：11

共 62 条

[1] Effects of Allogeneic Red Blood Cell Transfusions on Clinical Outcomes in Patients Undergoing Colorectal Cancer Surgery A Systematic Review and Meta-Analysis [J].

Acheson, Austin G. ;

Brookes, Matthew J. ;

Spahn, Donat R. .

ANNALS OF SURGERY, 2012, 256 (02) :235-244

[2] THE INDUCTION OF IMMUNOLOGICAL HYPORESPONSIVENESS BY PREOPERATIVE DONOR-SPECIFIC TRANSFUSIONS AND CYCLOSPORINE IN HUMAN CADAVERIC TRANSPLANTS - A PRELIMINARY TRIAL [J].

ALEXANDER, JW ;

BABCOCK, GF ;

FIRST, MR ;

DAVIES, CB ;

MADDEN, RL ;

MUNDA, R ;

PENN, I ;

FIDLER, JP ;

COFER, BR ;

STEPHENS, G ;

SCHROEDER, TJ ;

HARIHARAN, S ;

CARDI, M ;

MANZLER, A ;

COHEN, L ;

MENDOZA, N ;

CLYNE, D ;

GIESE, F .

TRANSPLANTATION, 1992, 53 (02) :423-427

[3]

[Anonymous], 2016, Blood Facts and Statistics

[4] The effect of universal leukodepletion of packed red blood cells on postoperative infections in high-risk patients undergoing abdominal aortic surgery [J].

Baron, JF ;

Gourdin, M ;

Bertrand, M ;

Mercadier, A ;

Delort, J ;

Kieffer, E ;

Coriat, P .

ANESTHESIA AND ANALGESIA, 2002, 94 (03) :529-537

[5] Blood Cell Supernatant Potentiates LPS-Induced Proinflammatory Cytokine Response From Peripheral Blood Mononuclear Cells [J].

Baumgartner, Joel M. ;

Nydam, Trevor L. ;

Clarke, Jason H. ;

Banerjee, Anirban ;

Silliman, Christopher C. ;

McCarter, Martin D. .

JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, 2009, 29 (06) :333-338

[6] Resuscitation with washed aged packed red blood cell units decreases the proinflammatory response in mice after hemorrhage [J].

Belizaire, Ritha M. ;

Makley, Amy T. ;

Campion, Eric M. ;

Sonnier, Dennis I. ;

Goodman, Michael D. ;

Dorlac, Warren C. ;

Friend, Lou Ann ;

Lentsch, Alex B. ;

Pritts, Timothy A. .

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 2012, 73 :S128-S133

[7] Microparticles from Stored Red Blood Cells Activate Neutrophils and Cause Lung Injury after Hemorrhage and Resuscitation [J].

Belizaire, Ritha M. ;

Prakash, Priya S. ;

Richter, Jillian R. ;

Robinson, Bryce R. ;

Edwards, Michael J. ;

Caldwell, Charles C. ;

Lentsch, Alex B. ;

Pritts, Timothy A. .

JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2012, 214 (04) :648-655

[8] Immunosuppression in Patients Who Die of Sepsis and Multiple Organ Failure [J].

Boomer, Jonathan S. ;

To, Kathleen ;

Chang, Kathy C. ;

Takasu, Osamu ;

Osborne, Dale F. ;

Walton, Andrew H. ;

Bricker, Traci L. ;

Jarman, Stephen D., II ;

Kreisel, Daniel ;

Krupnick, Alexander S. ;

Srivastava, Anil ;

Swanson, Paul E. ;

Green, Jonathan M. ;

Hotchkiss, Richard S. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2011, 306 (23) :2594-2605

[9] Current and emerging infectious risks of blood transfusions [J].

Busch, MP ;

Kleinman, SH ;

Nemo, GJ .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2003, 289 (08) :959-962

[10] Neutrophil priming, caused by cell membranes and microvesicles in packed red blood cell units, is abrogated by leukocyte depletion at collection [J].

Cardo, Lisa J. ;

Wilder, Donna ;

Salata, Jeanne .

TRANSFUSION AND APHERESIS SCIENCE, 2008, 38 (02) :117-125

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