Enantioselective Henry Reaction Catalyzed by CuII Salt and Bipiperidine

被引：118

作者：

Noole, Artur ^{[1
]}

Lippur, Kristin ^{[1
]}

Metsala, Andrus ^{[1
]}

Lopp, Margus ^{[1
]}

Kanger, Tonis ^{[1
]}

机构：

[1] Tallinn Univ Technol, Dept Chem, EE-12618 Tallinn, Estonia

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2010年 / 75卷 / 04期

关键词：

ASYMMETRIC MICHAEL ADDITION; 3,3'-BIMORPHOLINE DERIVATIVES; NITROALDOL REACTIONS; COMPLEXES; ALDEHYDES; LIGANDS; ORGANOCATALYSTS; BIMORPHOLINE;

D O I：

10.1021/jo902664v

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A complex derived from the enantiomeric bipiperidine and copper(II) acetate hydrate is an efficient catalyst for the enantioselective Henry reaction. The easy availability of both catalyst components, mild reaction conditions, high yield, and good to excellent enantioselectivity make the catalyst useful for everyday practice.

引用

页码：1313 / 1316

页数：4

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