Risk of Skin Cancer among Patients with Chronic Kidney Disease Treated with Ultraviolet B Phototherapy for Uraemic Pruritus: A Nationwide Cohort Study

被引：11

作者：

Ko, Mei-Ju ^{[1
,2
]}

Huang, Jenq-Wen ^{[3
,4
]}

Wu, Hon-Yen ^{[3
,5
,6
,7
]}

Tsai, Wan-Chuan ^{[5
,6
]}

Hsu, Le-Yin ^{[6
]}

Tsai, Ping-Hsiu ^{[5
]}

Chien, Kuo-Liong ^{[3
,6
]}

Hung, Kuan-Yu ^{[3
,8
]}

机构：

[1] Taipei City Hosp, Dept Dermatol, Taipei, Taiwan

[2] Natl Taiwan Univ Hosp & Coll Med, Dept Dermatol, Taipei, Taiwan

[3] Natl Taiwan Univ Hosp & Coll Med, Dept Internal Med, Taipei, Taiwan

[4] Natl Taiwan Univ Hosp, Dept Internal Med, Yunlin Branch, Touliu, Yunlin, Taiwan

[5] Far Eastern Mem Hosp, Dept Internal Med, New Taipei, Taiwan

[6] Natl Taiwan Univ, Inst Epidemiol & Prevent Med, Taipei, Taiwan

[7] Natl Yang Ming Chiao Tung Univ, Sch Med, Fac Med, Taipei, Taiwan

[8] Natl Taiwan Univ Hosp, Hsin Chu Branch, Dept Internal Med, Hsinchu, Taiwan

来源：

ACTA DERMATO-VENEREOLOGICA | 2021年 / 101卷

关键词：

UVB phototherapy; skin cancer; uraemic pruritus; chronic kidney disease;

D O I：

10.2340/00015555-3758

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The safety of ultraviolet B (UVB) phototherapy with respect to cutaneous carcinogenesis has not been established for patients with chronic kidney disease. To investigate this issue, a nationwide cohort study of 10,805 patients with advanced chronic kidney disease was conducted using data from the National Health Insurance of Taiwan, the Taiwan Cancer Registry, and the national death registry. After a median follow-up of 75 months, 16 of 2,161 patients in the UVB group and 63 of 8,644 patients in the non-UVB group developed skin cancers. Compared with the non-UVB group, patients in the UVB group did not show an increased risk of skin cancer (hazard ratio 1.066; 95% confidence interval 0.584-1.944), non-melanoma skin cancer (hazard ratio 1.067; 95% confidence interval 0.571-1.996), or cutaneous melanoma (hazard ratio 1.009; 95% confidence interval 0.115-8.879). In addition, patients who received more UVB phototherapy did not show an increased risk of skin cancer. UVB phototherapy appears to be a safe treatment for uraemic pruritus in patients with chronic kidney disease.

引用

页码：1 / 6

页数：6

共 50 条

[41] Prevalence and risk factors for cardiovascular disease among chronic kidney disease patients: results from the Chinese cohort study of chronic kidney disease (C-STRIDE) [J].

Yuan, Jun ;

Zou, Xin-Rong ;

Han, Si-Ping ;

Cheng, Hong ;

Wang, Lan ;

Wang, Jin-Wei ;

Zhang, Lu-Xia ;

Zhao, Ming-Hui ;

Wang, Xiao-Qin .

BMC NEPHROLOGY, 2017, 18

[42] Cardiometabolic risk phenotypes and chronic kidney disease incidence in older adults: a nationwide longitudinal cohort study [J].

Zeng, Zhihe ;

Xiao, Zhaoyang .

BMC PUBLIC HEALTH, 2025, 25 (01)

[43] Prevalence and risk factors for cardiovascular disease among chronic kidney disease patients: results from the Chinese cohort study of chronic kidney disease (C-STRIDE) [J].

Jun Yuan ;

Xin-Rong Zou ;

Si-Ping Han ;

Hong Cheng ;

Lan Wang ;

Jin-Wei Wang ;

Lu-Xia Zhang ;

Ming-Hui Zhao ;

Xiao-Qin Wang .

BMC Nephrology, 18

[44] Risk of Skin Cancer in Patients with Pterygium: A Nationwide Population-Based Cohort Study in Taiwan [J].

Yu, Han-Chieh ;

Lin, Cheng-Li ;

Chen, Zoe Tzu-Yi ;

Hu, Fung-Rong ;

Sung, Fung-Chang ;

Wang, I-Jong .

OCULAR SURFACE, 2014, 12 (01) :69-76

[45] A nationwide cohort study suggests chronic hepatitis B virus infection increases the risk of end-stage renal disease among patients in Taiwan [J].

Chen, Yi-Chun ;

Su, Yu-Chieh ;

Li, Chung-Yi ;

Wu, Chia-Pin ;

Lee, Moon-Sing .

KIDNEY INTERNATIONAL, 2015, 87 (05) :1030-1038

[46] Risk of incident chronic kidney disease and end-stage renal disease in patients with psoriasis: A nationwide population-based cohort study [J].

Chi, Ching-Chi ;

Wang, Jui ;

Chen, Yu-Fen ;

Wang, Shu-Hui ;

Chen, Fu-Li ;

Tung, Tao-Hsin .

JOURNAL OF DERMATOLOGICAL SCIENCE, 2015, 78 (03) :232-238

[47] A nationwide prospective cohort study of patients with advanced chronic kidney disease in Japan: The Reach-J CKD cohort study [J].

Junichi Hoshino ;

Kei Nagai ;

Hirayasu Kai ;

Chie Saito ;

Yukiko Ito ;

Koichi Asahi ;

Masahide Kondo ;

Kunitoshi Iseki ;

Chiho Iseki ;

Hirokazu Okada ;

Naoki Kashihara ;

Ichiei Narita ;

Takashi Wada ;

Christian Combe ;

Ronald L. Pisoni ;

Bruce M. Robinson ;

Kunihiro Yamagata .

Clinical and Experimental Nephrology, 2018, 22 :309-317

[48] A nationwide prospective cohort study of patients with advanced chronic kidney disease in Japan: The Reach-J CKD cohort study [J].

Hoshino, Junichi ;

Nagai, Kei ;

Kai, Hirayasu ;

Saito, Chie ;

Ito, Yukiko ;

Asahi, Koichi ;

Kondo, Masahide ;

Iseki, Kunitoshi ;

Iseki, Chiho ;

Okada, Hirokazu ;

Kashihara, Naoki ;

Narita, Ichiei ;

Wada, Takashi ;

Combe, Christian ;

Pisoni, Ronald L. ;

Robinson, Bruce M. ;

Yamagata, Kunihiro .

CLINICAL AND EXPERIMENTAL NEPHROLOGY, 2018, 22 (02) :309-317

[49] The risk of chronic kidney disease development in adult patients with chronic hypoparathyroidism treated with rhPTH(1-84): A retrospective cohort study [J].

Rejnmark, Lars ;

Ayodele, Olulade ;

Lax, Angela ;

Mu, Fan ;

Swallow, Elyse ;

Gosmanova, Elvira O. .

CLINICAL ENDOCRINOLOGY, 2023, 98 (04) :496-504

[50] Metabolic dysfunction-associated fatty liver disease and risk of incident chronic kidney disease: A nationwide cohort study [J].

Jung, Chan-Young ;

Koh, Hee Byung ;

Park, Keun Hyung ;

Joo, Young Su ;

Kim, Hyung Woo ;

Ahn, Sang Hoon ;

Park, Jung Tak ;

Kim, Seung Up .

DIABETES & METABOLISM, 2022, 48 (04)

← 1 2 3 4 5 →