Chlorophyllide α/cyclodextrin interaction in aqueous solution

被引:4
作者
Dentuto, PL
Castagnolo, M
Catucci, L
Cosma, P
Fini, P
Agostiano, A
机构
[1] CNR, Ist & Proc Chim Fis, Sez Bari, I-70126 Bari, Italy
[2] Univ Bari, Dipartmento Chim, I-70126 Bari, Italy
关键词
chlide; hydroxypropyl-beta-cyclodextrin; hydroxyl-gamma-cyclodextrin; photodynamic therapy;
D O I
10.1023/B:JTAN.0000038984.85371.55
中图分类号
O414.1 [热力学];
学科分类号
摘要
The interactions between Chlorophyllide a (Chlide), a pigment having the same structure of Chl a without the phytilic tail, and two CDs having the same moieties but different cavity size, the hydroxypropyl-beta-cyclodextrin and the hydroxypropyl-gamma-cyclodextrin, were studied in aqueous solutions by means of absorption, fluorescence spectroscopy, circular dichroism and isothermal titration calorimetry. The results obtained indicate that both cyclodextrins are able to modify the aggregation equilibrium of the pigment favouring the monomeric form.
引用
收藏
页码:437 / 444
页数:8
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