Pediatric Cancer

被引：8

作者：

Baliga, Sujith ^{[1
]}

Yock, Torunn I. ^{[2
,3
]}

机构：

[1] Harvard Med Sch, Massachusetts Gen Hosp, Dept Radiat Oncol, Francis H Burr Proton Therapy Ctr, 30 Fruit St, Boston, MA 02114 USA

[2] Francis H Burr Proton Therapy Ctr, 30 Fruit St, Boston, MA 02114 USA

[3] Harvard Med Sch, Massachusetts Gen Hosp, Dept Radiat Oncol, 55 Fruit St, Boston, MA 02114 USA

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2020年 / 34卷 / 01期

关键词：

Pediatric cancer; Proton beam therapy; Survivorship; CENTRAL-NERVOUS-SYSTEM; PHASE-II TRIAL; GERM-CELL TUMORS; ATYPICAL TERATOID/RHABDOID TUMORS; LOCALIZED EWING SARCOMA; HISTOLOGY WILMS-TUMOR; RADIATION-THERAPY; PROTON RADIOTHERAPY; CHILDHOOD MEDULLOBLASTOMA; CRANIOSPINAL RADIOTHERAPY;

D O I：

10.1016/j.hoc.2019.08.021

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In pediatric brain tumors, the intensification of chemotherapy has allowed for a reduction in radiotherapy (RI) volume to an involved field approach, particularly in patients with medulloblastoma. For patients with low-grade gliomas, the trend has remained to delay RT with chemotherapy; however, when RT is used, typically smaller clinical target volume margins are used. For patients with extracranial tumors, intensive chemotherapy to address systemic disease with local control is considered standard. Proton beam therapy shows significant promise in addressing both short-term and long-term toxicities in both central nervous system (CNS) and non-CNS pediatric tumors.

引用

页码：143 / +

页数：18

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