Supercritical CO2 extraction of α-/β-amyrin from uvaia (Eugenia pyriformis Cambess.): Effects of pressure and co-solvent addition

被引：16
作者：
Klein, Elissandro Jair [1 ]
Nathia-Neves, Grazielle [2 ]
Vardanega, Renata [2 ]
Meireles, M. Angela A. [2 ]
da Silvan, Edson Antonio [3 ]
Adeodato Vieira, Melissa Gurgel [1 ]
机构：
[1] Univ Estadual Campinas, UNICAMP, Sch Chem Engn, Ave Albert Einstein 500, BR-13083852 Campinas, SP, Brazil
[2] Univ Estadual Campinas, UNICAMP, Sch Food Engn, LASEFI Dept Food Engn, R Monteiro Lobato 80, BR-13083862 Campinas, SP, Brazil
[3] Western Parana State Univ, Ctr Engn & Exact Sci, Rua Fac 645, BR-85903000 Toledo, PR, Brazil
来源：
JOURNAL OF SUPERCRITICAL FLUIDS | 2019年 / 153卷
基金：
巴西圣保罗研究基金会;
关键词：
Eugenia pyriformis Cambess; Supercritical fluid extraction; Co-solvent; alpha-Amyrin; beta-Amyrin; FLUID EXTRACTION; BETA-AMYRIN; ANTIOXIDANT; SEPARATION; TRITERPENE; ETHANOL; LIQUID; LEAVES; OIL;
D O I：
10.1016/j.supflu.2019.104595
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The obtaining of alpha-/beta-amyrin from Eugenia pyriformis leaves is a subject with few studies that needs to be explored further in order to extend the understanding about processes to recover these compounds. Thus, the objective of this study was to evaluate the effects of pressure and co-solvent addition in the supercritical CO2 extraction regarding the global extraction yield, alpha-/beta-amyrin purity and yield, and antioxidant activity. Extractions were performed at pressures varying in the range 15-30 MPa at fixed temperature of 60 degrees C. The effect of co-solvent was evaluated at 5 and 15% (w/w) of ethyl acetate and ethanol. The best pressure for increasing alpha-/beta-amyrin yield was 20 MPa. The co-solvent addition increased the global extraction and alpha-/beta-amyrin yields, achieving a yield of 16.12 mg g(-1) RM (raw material) by using 15% ethanol, while the highest alpha-/beta-amyrin purity was obtained by using 5% of ethyl acetate as co-solvent. (C) 2019 Elsevier B.V. All rights reserved.
引用
收藏
页数：6
相关论文
共 37 条
[1]   Extraction of Mentha spicata L. Volatile Compounds: Evaluation of Process Parameters and Extract Composition [J].
Almeida, Priscilla P. ;
Mezzomo, Natalia ;
Ferreira, Sandra R. S. .
FOOD AND BIOPROCESS TECHNOLOGY, 2012, 5 (02) :548-559
[2]  
[Anonymous], 1981, Official Methods of Analysis, V13th
[3]   Development, Physicochemical Characterization and In Vitro Anti-Inflammatory Activity of Solid Dispersions of α,β Amyrin Isolated from Protium Oilresin [J].
da Silva Junior, Walter Ferreira ;
de Oliveira Pinheiro, Jonas Gabriel ;
Bezerra de Menezes, Danielle Lima ;
de Sobral e Silva, Natan Emanuell ;
Oliveira de Almeida, Patricia Danielle ;
Lima, Emerson Silva ;
da Veiga Junior, Valdir Florencio ;
de Azevedo, Eduardo Pereira ;
Neves de Lima, Adley Antonini .
MOLECULES, 2017, 22 (09)
[4]   Supercritical fluid extraction of bioactive compounds [J].
da Silva, Rui P. F. F. ;
Rocha-Santos, Teresa A. P. ;
Duarte, Armando C. .
TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2016, 76 :40-51
[5]   Wild Brazilian species of Eugenia genera (Myrtaceae) as an innovation hotspot for food and pharmacological purposes [J].
de Araujo, Fabio Fernandes ;
Neri-Numa, Iramaia Angelica ;
Farias, David de Paulo ;
Miranda Castro da Cunha, Gabryelle Rahyara ;
Pastore, Glaucia Maria .
FOOD RESEARCH INTERNATIONAL, 2019, 121 :57-72
[6]   Supercritical fluid extraction of vegetable matrices: Applications, trends and future perspectives of a convincing green technology [J].
de Melo, M. M. R. ;
Silvestre, A. J. D. ;
Silva, C. M. .
JOURNAL OF SUPERCRITICAL FLUIDS, 2014, 92 :115-176
[7]   SEMI-PREPARATIVE SEPARATION OF α AND β-AMYRIN BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC [J].
Dias, Marluce Oliveira ;
Hamerski, Lidilhone ;
Pinto, Angelo C. .
QUIMICA NOVA, 2011, 34 (04) :704-U161
[8]  
Enujiugha V. N., 2012, Food and Nutrition Sciences, V3, P7
[9]  
Farias-Campomanes Angela M., 2013, Recent Patents on Engineering, V7, P41, DOI [10.2174/1872212111307010004, DOI 10.2174/1872212111307010004]
[10]   Supercritical fluid extraction of Alnus glutinosa (L.) Gaertn. [J].
Felfoeldi-Gava, Aniko ;
Szarka, Szabolcs ;
Simandi, Bela ;
Blazics, Balazs ;
Simon, Blanka ;
Kery, Agnes .
JOURNAL OF SUPERCRITICAL FLUIDS, 2012, 61 :55-61
1234