Nutritional Influences on Epigenetic Programming Asthma, Allergy, and Obesity

被引：17

作者：

Palmer, Debra J. ^{[1
]}

Huang, Rae-Chi ^{[2
]}

Craig, Jeffrey M. ^{[3
,4
]}

Prescott, Susan L. ^{[1
,2
]}

机构：

[1] Univ Western Australia M561, Sch Paediat & Child Hlth, Subiaco, WA 6008, Australia

[2] Univ Western Australia, Telethon KIDS Inst, Subiaco, WA 6008, Australia

[3] Univ Melbourne, Dept Paediat, Parkville, Vic 3052, Australia

[4] Royal Childrens Hosp, Murdoch Childrens Res Inst, Early Life Epigenet Grp, Parkville, Vic 3052, Australia

来源：

IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA | 2014年 / 34卷 / 04期

关键词：

Nutrition; Early life; Epigenetic regulation; Asthma; Allergy; Obesity; FISH-OIL SUPPLEMENTATION; FATTY-ACID SUPPLEMENTATION; DNA METHYLATION; FOLIC-ACID; GUT MICROBIOTA; HIGH-RISK; DEVELOPMENTAL ORIGINS; PROMOTER METHYLATION; IMMUNE-RESPONSES; CHILDHOOD ASTHMA;

D O I：

10.1016/j.iac.2014.07.003

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Observational studies show consistent links between early-life nutritional exposures as important risk factors for the development of asthma, allergy, and obesity. Reliance on increasing use of dietary supplementation and fortification (eg, with folate) to compensate for increased consumption of processed foods is also influencing immune and metabolic outcomes. Epigenetics is providing substantial advances in understanding how early-life nutritional exposures can effect disease development. This article summarizes current evidence linking the influence of early-life nutritional exposures on epigenetic regulation with a focus on the disease outcomes of asthma, allergy, and obesity.

引用

页码：825 / +

页数：14

共 92 条

[61] Vitamin D has wide regulatory effects on histone demethylase genes [J].

Pereira, Fabio ;

Barbachano, Antonio ;

Singh, Prashant K. ;

Campbell, Moray J. ;

Munoz, Alberto ;

Jesus Larriba, Maria .

CELL CYCLE, 2012, 11 (06) :1081-1089

[62] Insulin-like Growth Factor 2/H19 Methylation at Birth and Risk of Overweight and Obesity in Children [J].

Perkins, Ellen ;

Murphy, Susan K. ;

Murtha, Amy P. ;

Schildkraut, Joellen ;

Jirtle, Randy L. ;

Demark-Wahnefried, Wendy ;

Forman, Michele R. ;

Kurtzberg, Joanne ;

Overcash, Francine ;

Huang, Zhiqing ;

Hoyo, Cathrine .

JOURNAL OF PEDIATRICS, 2012, 161 (01) :31-39

[63]

Prescott SL, 1998, CLIN EXP ALLERGY, V28, P1313

[64] Food allergy: Riding the second wave of the allergy epidemic [J].

Prescott, Susan ;

Allen, Katrina J. .

PEDIATRIC ALLERGY AND IMMUNOLOGY, 2011, 22 (02) :155-160

[65] Maternal fish oil supplementation in pregnancy modifies neonatal leukotriene production by cord-blood-derived neutrophils [J].

Prescott, Susan L. ;

Barden, Anne E. ;

Mori, Trevor A. ;

Dunstan, Janet A. .

CLINICAL SCIENCE, 2007, 113 (9-10) :409-416

[66] Early-life environmental determinants of allergic diseases and the wider pandemic of inflammatory noncommunicable diseases [J].

Prescott, Susan L. .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2013, 131 (01) :23-30

[67] Differential epigenome-wide DNA methylation patterns in childhood obesity-associated asthma [J].

Rastogi, Deepa ;

Suzuki, Masako ;

Greally, John M. .

SCIENTIFIC REPORTS, 2013, 3

[68] Probiotics Modulate Host-Microbe Interaction in the Placenta and Fetal Gut: A Randomized, Double-Blind, Placebo-Controlled Trial [J].

Rautava, Samuli ;

Carmen Collado, Maria ;

Salminen, Seppo ;

Isolauri, Erika .

NEONATOLOGY, 2012, 102 (03) :178-184

[69]

Ravelli ACJ, 1999, AM J CLIN NUTR, V70, P811

[70] Effects of short chain fatty acid producing bacteria on epigenetic regulation of FFAR3 in type 2 diabetes and obesity [J].

Remely, Marlene ;

Aumueller, Eva ;

Merold, Christine ;

Dworzak, Simone ;

Hippe, Berit ;

Zanner, Julia ;

Pointner, Angelika ;

Brath, Helmut ;

Haslberger, Alexander G. .

GENE, 2014, 537 (01) :85-92

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