Gluten-dependent diabetes-related and thyroid-related autoantibodies in patients with celiac disease

被引:162
作者
Ventura, A
Neri, E
Ughi, C
Leopaldi, A
Città, A
Not, T
机构
[1] Univ Trieste, IRCCS Burlo Garofolo, Ist Clin Pediat, Pediat Clin, I-34100 Trieste, Italy
[2] Univ Trieste, IRCCS Burlo Garofolo, Lab Anal, I-34100 Trieste, Italy
[3] Univ Pisa, Dipartimento Pediat, Pisa, Italy
关键词
D O I
10.1067/mpd.2000.107160
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Patients with celiac disease are at high risk of having autoimmune disorders. Moreover, untreated patients with celiac disease have been found to have a higher than expected prevalence of organ-specific autoantibodies. In a prospective study of 90 patients with celiac disease, we found that the prevalence of diabetes and thyroid-related serum antibodies was 11.1% and 14.4%, respectively. Like antiendomysium autoantibodies, these organ-specific antibodies seem to be gluten-dependent and tend to disappear during a gluten-free diet.
引用
收藏
页码:263 / 265
页数:3
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