Ammonium and phosphate limitation in 1,3-propanediol production by Klebsiella pneumoniae

被引：10

作者：

Zheng, Zong-Ming ^{[1
]}

Xu, Yun-Zhen ^{[2
]}

Wang, Ti-Peng ^{[1
]}

Dong, Chang-Qing ^{[1
]}

Yang, Yong-Ping ^{[1
]}

Liu, De-Hua ^{[2
]}

机构：

[1] N China Elect Univ, Sch Renewable Energy, Natl Engn Lab Power Generat Equipment, Beijing 102206, Peoples R China

[2] Tsinghua Univ, Dept Chem Engn, Beijing 100084, Peoples R China

来源：

BIOTECHNOLOGY LETTERS | 2010年 / 32卷 / 02期

关键词：

Ammonium limitation; Fermentation; Klebsiella pneumoniae; Phosphate limitation; 1,3-Propanediol; MICROBIAL-GROWTH; FERMENTATION; GLYCEROL; SUBSTRATE; CULTURE; PATHWAY;

D O I：

10.1007/s10529-009-0150-y

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Excretion of 1,3-propanediol (1,3-PD) by K. pneumoniae was compared in ammonium- and phosphate-limited chemostat cultures running with an excess of glycerol. 59 and 43% catabolic flux were directed to 1,3-PD in ammonia-limited cultures and phosphate-limited cultures at dilution rate of 0.1 h(-1), respectively. Ammonia-limited fed-batch cultures produced 61 g 1,3-PD l(-1) and a total of 15 g l(-1) organic acid in 36 h. However, phosphate-limited fed-batch cultures excreted 61 g lactate l(-1) and 44 g 1,3-PD l(-1).

引用

页码：289 / 294

页数：6

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