Synthesis and antipsychotic and anticonvulsant activity of some new substituted oxa/thiadiazolylazetidinonyl/thiazolidinonylcarbazoles

被引：101

作者：

Kaur, Hemlata ^{[1
]}

Kumar, Sunil ^{[1
]}

Vishwakarma, Pinki ^{[1
]}

Sharma, Monica ^{[1
]}

Saxena, K. K. ^{[1
]}

Kumar, Ashok ^{[1
]}

机构：

[1] LLRM Med Coll, Dept Pharmacol, Div Med Chem, Meerut 250004, Uttar Pradesh, India

来源：

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | 2010年 / 45卷 / 07期

关键词：

Oxa/thiadiazolyl-azetidinonyl carbazoles; Oxa/thiadiazolyl-thiazolidinonyl carbazoles; Antipsychotic activity; Anticonvulsant activity; Acute toxicity; ANTAGONIST; ANALOGS; AGENTS;

D O I：

10.1016/j.ejmech.2010.02.060

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A novel substituted oxa/thiadiazolylazetidinonyl/thiazolidinonylcarbazoles (4a-j), (5a-j) and (6a-j) were synthesized and screened for their antipsychotic and anticonvulsant activities. It is concluded from the results compound 6j showed promising antipsychotic as well as anticonvulsant activity. (C) 2010 Elsevier Masson SAS. All rights reserved.

引用

页码：2777 / 2783

页数：7

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