Emergence of Resistance to Third-Generation Cephalosporin in Shigella-A Case Report

被引：12

作者：

Mandal, Jharna ^{[1
]}

Mondal, Nivedita ^{[2
]}

Mahadevan, S. ^{[2
]}

Parija, Subhash Chandra ^{[1
]}

机构：

[1] Jawaharlal Inst Postgrad Med Educ & Res, Dept Microbiol, Pondicherry 605006, India

[2] Jawaharlal Inst Postgrad Med Educ & Res, Dept Paediat, Pondicherry 605006, India

来源：

JOURNAL OF TROPICAL PEDIATRICS | 2010年 / 56卷 / 04期

关键词：

third generation; Cephalosporin resistant; Shigella; Puducherry; SPECTRUM BETA-LACTAMASE; BURDEN; INDIA; SPP;

D O I：

10.1093/tropej/fmp118

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

The emergence of ciprofloxacin resistance in Shigella has shifted the attention to cephalosporins. The first occurrence of third generation cephalosporin-resistant Shigella flexneri was from France. This article reports the first case of cephalosporin-resistant S. flexneri from India. A 12-month-old child was admitted for a 20-day episode of loose stools, non-fetid, with mucus and blood. The stool sample showed the presence of blood and mucus and S. flexneri which was resistant to Ampicillin, Nalidixic acid, Ciprofloxacin, Furoxone, Ceftriaxone and sensitive only to Cefoperazone and sulbactam combination. The child was promptly admitted and treated with a combination of Cefoperazone and sulbactam. The use of this combination was met with success in the present case, and may be considered as a temporary answer to the emerging cephalosporin-resistance.

引用

页码：278 / 279

页数：2

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