Management of gynaecomastia: an update

被引:45
作者
Gikas, P.
Mokbel, K.
机构
[1] Brunel Inst Canc Genet, London W1M 3FD, England
[2] Princess Grace Hosp, London W1M 3FD, England
[3] Univ London St Georges Hosp, London, England
关键词
D O I
10.1111/j.1742-1241.2006.01095.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Gynaecomastia, a benign enlargement of the male breast as a result of proliferation of the glandular component, is common, being present in 30-50% of healthy men. It may be an incidental finding, an acute unilateral or bilateral tender breast enlargement or a progressive painless enlargement of the male breast. A general medical history and careful physical examination, looking for features suggestive of breast cancer, often suffice for evaluation in patients without symptoms or those with incidentally discovered breast enlargement. If the gynaecomastia is of recent onset, a more detailed evaluation, including selected laboratory tests to search for an underlying cause is necessary. Treatment depends on the cause: an offending drug may need to be withdrawn or alternatively radiation, surgery and/or medical therapy may be necessary. The use of a combination of surgical excision and liposuction through a periareolar incision represents the surgical approach of choice.
引用
收藏
页码:1209 / 1215
页数:7
相关论文
共 39 条
[1]  
ALAGARATNAM TT, 1987, CLIN THER, V9, P483
[2]  
ANDERSEN JA, 1982, ACTA PATH MICRO IM A, V90, P191
[3]   Gynecomastia: Its features, and when and how to treat it [J].
Bembo, SA ;
Carlson, HE .
CLEVELAND CLINIC JOURNAL OF MEDICINE, 2004, 71 (06) :511-517
[4]   Evaluation of tamoxifen and anastrozole in the prevention of gynecomastia and breast pain induced by bicalutamide monotherapy of prostate cancer [J].
Boccardo, F ;
Rubagotti, A ;
Battaglia, M ;
Di Tonno, P ;
Selvaggi, FP ;
Conti, G ;
Comeri, G ;
Bertaccini, A ;
Martorana, G ;
Galassi, P ;
Zattoni, F ;
Macchiarella, A ;
Siragusa, A ;
Muscas, G ;
Durand, F ;
Potenzoni, D ;
Manganelli, A ;
Ferraris, V ;
Montefiore, F .
JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (04) :808-815
[5]   Aromatase and gynecomastia [J].
Braunstein, GD .
ENDOCRINE-RELATED CANCER, 1999, 6 (02) :315-324
[6]  
BRAUNSTEIN GD, 1993, NEW ENGL J MED, V328, P490
[7]  
CARLSON HE, 1992, ENDOCRINOL METAB, P294
[8]  
Daniels IR, 2001, EUR J SURG, V167, P885
[9]   Management of gynaecomastia in patients with prostate cancer:: a systematic review [J].
Di Lorenzo, G ;
Autorino, R ;
Perdonà, S ;
De Placido, S .
LANCET ONCOLOGY, 2005, 6 (12) :972-979
[10]  
EAVES FF, 1995, CLIN PLAST SURG, V22, P683