Understanding and overcoming major barriers in cancer nanomedicine

被引：124
作者：
Nie, Shumine [1 ,2 ,3 ]
机构：
[1] Emory Univ, Dept Biomed Engn, Atlanta, GA 30322 USA
[2] Emory Univ, Dept Chem, Atlanta, GA 30322 USA
[3] Georgia Inst Technol, Atlanta, GA 30322 USA
来源：
NANOMEDICINE | 2010年 / 5卷 / 04期
关键词：
TUMOR VASCULAR-PERMEABILITY; MACROMOLECULAR THERAPEUTICS; POLYMERIC NANOPARTICLES; PROTEIN ADSORPTION; BIODISTRIBUTION; NANOTECHNOLOGY; DELIVERY; THERAPY; CORONA; PHARMACOKINETICS;
D O I：
10.2217/NNM.10.23
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
引用
收藏
页码：523 / 528
页数：6
相关论文
共 51 条
[1]   The use of nanocrystals in biological detection [J].
Alivisatos, P .
NATURE BIOTECHNOLOGY, 2004, 22 (01) :47-52
[2]   Impact of tumor-specific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality in vivo imaging [J].
Bartlett, Derek W. ;
Su, Helen ;
Hildebrandt, Isabel J. ;
Weber, Wolfgang A. ;
Davis, Mark E. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (39) :15549-15554
[3]   Nanoparticle and targeted systems for cancer therapy [J].
Brannon-Peppas, L ;
Blanchette, JO .
ADVANCED DRUG DELIVERY REVIEWS, 2004, 56 (11) :1649-1659
[4]   Detailed identification of plasma proteins adsorbed on copolymer nanoparticles [J].
Cedervall, Tommy ;
Lynch, Iseult ;
Foy, Martina ;
Berggard, Tord ;
Donnelly, Seamas C. ;
Cagney, Gerard ;
Linse, Sara ;
Dawson, Kenneth A. .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007, 46 (30) :5754-5756
[5]   Understanding the nanoparticle-protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles [J].
Cedervall, Tommy ;
Lynch, Iseult ;
Lindman, Stina ;
Berggard, Tord ;
Thulin, Eva ;
Nilsson, Hanna ;
Dawson, Kenneth A. ;
Linse, Sara .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (07) :2050-2055
[6]   The transferrin receptor part I: Biology and targeting with cytotoxic antibodies for the treatment of cancer [J].
Daniels, Tracy R. ;
Delgado, Tracie ;
Rodriguez, Jose A. ;
Helguera, Gustavo ;
Penichet, Manuel L. .
CLINICAL IMMUNOLOGY, 2006, 121 (02) :144-158
[7]   Selective gene delivery for cancer therapy using cationic liposomes: In vivo proof of applicability [J].
Dass, Crispin R. ;
Choong, Peter F. M. .
JOURNAL OF CONTROLLED RELEASE, 2006, 113 (02) :155-163
[8]   Cellular dynamics of EGF receptor-targeted synthetic viruses [J].
de Bruin, Karla ;
Ruthardt, Nadia ;
von Gersdorff, Katharina ;
Bausinger, Ralf ;
Wagner, Ernst ;
Ogris, Manfred ;
Braeuchle, Christoph .
MOLECULAR THERAPY, 2007, 15 (07) :1297-1305
[9]   Immunological properties of engineered nanomaterials [J].
Dobrovolskaia, Marina A. ;
Mcneil, Scott E. .
NATURE NANOTECHNOLOGY, 2007, 2 (08) :469-478
[10]   Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers [J].
Dreher, MR ;
Liu, WG ;
Michelich, CR ;
Dewhirst, MW ;
Yuan, F ;
Chilkoti, A .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2006, 98 (05) :335-344
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