Hepatitis, hyperglycemia, pleural effusion, eosinophilia, hematuria and proteinuria occurring early in clozapine treatment

被引：40
作者：
Thompson, J
Chengappa, KNR
Good, CB
Baker, RW
Kiewe, RP
Bezner, J
Schooler, NR
机构：
[1] Univ Pittsburgh, Sch Med, Pittsburgh, PA USA
[2] Univ Pittsburgh, Med Ctr, Mayview State Hosp, Sch Med,Special Studies Ctr, Pittsburgh, PA USA
[3] Univ Pittsburgh, Med Ctr, Western Psychiat Inst & Clin, Pittsburgh, PA USA
[4] Univ Pittsburgh, Vet Affairs Med Ctr, Dept Med, Pittsburgh, PA USA
[5] Univ Mississippi, Med Ctr, Dept Psychiat & Human Behav, University, MS 38677 USA
来源：
INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY | 1998年 / 13卷 / 02期
关键词：
clozapine; hematuria and proteinuria; hepatitis; hyperglycemia; pleural effusions;
D O I：
10.1097/00004850-199803000-00007
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
This report describes a 48-year-old caucasian male with schizophrenia who developed hepatitis, hyperglycemia, pleural effusion, eosinophilia, hematuria and proteinuria early in clozapine treatment which resolved on drug discontinuation. The literature on similar cases is reviewed. (C) 1998 Rapid Science Ltd.
引用
收藏
页码：95 / 98
页数：4
相关论文
共 15 条
[1]  
BALDESSARINI R, 1992, NEW ENGL J MED, V324, P746
[2]   Recurrent pancreatitis on clozapine re-challenge [J].
Chengappa, KNR ;
Pelucio, M ;
Baker, RW ;
Cole, D .
JOURNAL OF PSYCHOPHARMACOLOGY, 1995, 9 (04) :381-382
[3]  
DALY JM, 1992, AM J PSYCHIAT, V149, P1274
[4]   CLOZAPINE RECHALLENGE AFTER MARKED LIVER-ENZYME ELEVATION [J].
EGGERT, AE ;
CRISMON, ML ;
DORSON, PG ;
TAYLOR, RL .
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 1994, 14 (06) :425-426
[5]   EOSINOPHILIA, CLOZAPINE, AND PANCREATITIS [J].
FRANKENBURG, FR ;
KANDO, J .
LANCET, 1992, 340 (8813) :251-251
[6]   SIDE-EFFECTS OF CLOZAPINE [J].
GAERTNER, HJ ;
FISCHER, E ;
HOSS, J .
PSYCHOPHARMACOLOGY, 1989, 99 :S97-S100
[7]  
KAMRAN A, 1994, AM J PSYCHIAT, V151, P1395
[8]  
KELLNER M, 1993, AM J PSYCHIAT, V150, P985
[9]   Ketoacidosis as a side-effect of clozapine: A case report [J].
Kostakoglu, AE ;
Yazici, KM ;
Erbas, T ;
Guvener, N .
ACTA PSYCHIATRICA SCANDINAVICA, 1996, 93 (03) :217-218
[10]  
KOVAL MS, 1994, AM J PSYCHIAT, V151, P1520
12