Pigmented poroid neoplasm mimicking nodular melanoma

被引:3
作者
Mitsuishi, Tsuyoshi [1 ]
Ansai, Shin-ichi [1 ]
Ueno, Takashi [1 ]
Kawana, Seiji [1 ]
机构
[1] Nippon Med Sch, Dept Dermatol, Bunkyo Ku, Tokyo 1138603, Japan
关键词
5-S-cysteinyldopa; nodular melanoma; pigmented; poroid neoplasm; ECCRINE POROMA; MECHANISM; MELANOCYTES; EXPRESSION;
D O I
10.1111/j.1346-8138.2010.00844.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
We reported the case of a 92-year-old woman with a pigmented and non-pigmented surface of the pedunculated nodule on her lower leg. Microscopic examination revealed that this nodule consisted of a component of small, dark, homogenous, poroid cells and cuticular cells in the dermis. The histopathological features of the lesion were consistent with poroid neoplasm. Immunohistochemistry showed that HMB-45 and Melan-A were positive in malanocytes and melanophages of the pigmented areas. Unlike most poroid neoplasms, this case showed pigmented lesion mimicked nodular melanoma.
引用
收藏
页码:542 / 544
页数:3
相关论文
共 12 条
[1]  
Abenoza P, 1990, Neoplasms with eccrine differentiation
[2]   Origin of poroid hidradenoma and pigmentation mechanism of eccrine poroma: critical analysis of an unique presentation [J].
Chiu, H-H ;
Chen, P-H ;
Wu, C-Sh ;
Chen, G-S ;
Tsai, K-B ;
Wen, C-H ;
Lan, C-C E. .
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2009, 23 (05) :597-599
[3]   The epidermal stem cell factor is over-expressed in lentigo senilis: Implication for the mechanism of hyperpigmentation [J].
Hattori, H ;
Kawashima, M ;
Ichikawa, Y ;
Imokawa, G .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2004, 122 (05) :1256-1265
[4]   Autocrine and paracrine regulation of melanocytes in human skin and in pigmentary disorders [J].
Imokawa, G .
PIGMENT CELL RESEARCH, 2004, 17 (02) :96-110
[5]  
JIN K, 1990, Journal of Dermatology (Tokyo), V17, P555
[6]   Pigmented eccrine poroma: A report of two cases and study with dermatoscopy [J].
Kuo, HW ;
Ohara, K .
DERMATOLOGIC SURGERY, 2003, 29 (10) :1076-1079
[7]   Pigmented eccrine poroma with enhanced endothelin-1 expression: implications for mechanism of hyperpigmentation [J].
Lan, CCE ;
Yu, HS ;
Wu, CS ;
Tsai, KB ;
Wen, CH ;
Chen, GS .
BRITISH JOURNAL OF DERMATOLOGY, 2005, 152 (05) :1070-1072
[8]   The mechanism of hyperpigmentation in seborrhoeic keratosis involves the high expression of endothelin-converting enzyme-1α and TNF-α, which stimulate secretion of endothelin 1 [J].
Manaka, I ;
Kadono, S ;
Kawashima, M ;
Kobayashi, T ;
Imokawa, G .
BRITISH JOURNAL OF DERMATOLOGY, 2001, 145 (06) :895-903
[9]   PIGMENTED ECCRINE POROMA - A SIMULANT OF NODULAR MELANOMA [J].
MOUSAWI, A ;
KIBBI, AG .
INTERNATIONAL JOURNAL OF DERMATOLOGY, 1995, 34 (12) :857-858
[10]   Pigmented eccrine poroma occurring on the scalp - Derivation of melanocytes in the tumor [J].
Ohata, Utako ;
Hara, Hiroyuki ;
Suzuki, Hiroyuki .
AMERICAN JOURNAL OF DERMATOPATHOLOGY, 2006, 28 (02) :138-141